Invasive Candidiasis in Liver Transplant Recipients: a Review

被引：0

作者：

Sigler, Rachel ^{[1
]}

Aslam, Saima ^{[1
]}

机构：

[1] Univ Calif San Diego, Div Infect Dis & Global Publ Hlth, 4510 Execut Dr,MC7745, La Jolla, CA 92021 USA

来源：

CURRENT FUNGAL INFECTION REPORTS | 2021年 / 15卷 / 04期

关键词：

Liver transplant; Candida; Infection; Solid organ transplant; Invasive fungal infection; Fluconazole; T2; MAGNETIC-RESONANCE; FUNGAL-INFECTIONS; SOLID-ORGAN; ANTIFUNGAL PROPHYLAXIS; RISK-FACTORS; DOUBLE-BLIND; FLUCONAZOLE; AURIS; CANDIDEMIA; MANAGEMENT;

D O I：

10.1007/s12281-021-00426-6

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Purpose of Review This review summarizes the literature on invasive candidiasis (IC) in liver transplant recipients (LTRs) regarding diagnostic strategies, treatment, and prophylaxis. Recent Findings Recent literature on IC has expanded and refined definitions of risk factors for IC in LTRs. We discuss increasing rates of resistance among candida species and new antifungals. Diagnostic modalities continue to decrease time to initiation of empiric antifungals, which may impact outcomes. Summary A well-documented host of risk factors for IC may allow for targeted prophylaxis, while minimizing exposure to antifungal medications. Further research on minimum effective duration of treatment and prophylaxis is needed to combat resistance.

引用

页码：151 / 161

页数：11

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