Intraocular therapy in noninfectious uveitis

被引：16

作者：

Modugno, Rocco Luigi ^{[1
]}

Testi, Ilaria ^{[2
]}

Pavesio, Carlos ^{[2
,3
]}

机构：

[1] Univ Padua, Dept Neurosci, Ophthalmol Unit, Padua, Italy

[2] Moorfields Eye Hosp, Natl Hlth Serv Fdn Trust, 162 City Rd,Old St, London EC1V 2PD, England

[3] UCL, Inst Ophthalmol, Biomed Res Ctr, London, England

来源：

JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION | 2021年 / 11卷 / 01期

关键词：

Non-infectious uveitis; Local therapy; Intravitreal; Corticosteroids; Anti-vascular endothelial growth factor (VEGF); Immunosuppressive agents; Methotrexate; Biologics; Anti-tumor necrosis factor (TNF) alpha; INTRAVITREAL DEXAMETHASONE IMPLANT; MACULAR-EDEMA; TRIAMCINOLONE ACETONIDE; BEVACIZUMAB AVASTIN; POSTERIOR UVEITIS; INFLIXIMAB; METHOTREXATE; INTERMEDIATE; MULTICENTER; SIROLIMUS;

D O I：

10.1186/s12348-021-00267-x

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Systemic corticosteroids and immunosuppressant agents are the mainstay of therapy for non-infectious uveitis (NIU). However, the risks associated with systemic administration and the need of delivering an effective and safe anti-inflammatory treatment targeted to the site of inflammation have prompt the use of local therapy in the management of NIU. This review will analyse the different local treatment options available, including corticosteroids, anti-vascular endothelial growth factor (VEGF), methotrexate and the recent biologics.

引用

页数：8

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