Dynamics of coagulation factor XIII activity after video-assisted thoracoscopic lobectomy for non-small cell lung cancer

被引：3

作者：

Shirai, Suguru ^{[1
]}

Yamauchi, Yoshikane ^{[1
]}

Yokote, Fumi ^{[1
]}

Sakai, Takashi ^{[1
]}

Saito, Yuichi ^{[1
]}

Sakao, Yukinori ^{[1
]}

Kawamura, Masafumi ^{[1
]}

机构：

[1] Teikyo Univ, Dept Surg, Sch Med, Tokyo, Japan

来源：

JOURNAL OF THORACIC DISEASE | 2019年 / 11卷 / 12期

关键词：

Coagulation factor XIII (coagulation FXIII); non-small cell lung cancer (NSCLC); video-assisted thoracic surgery (VATS); surgical invasiveness; LONG-TERM OUTCOMES; VATS LOBECTOMY; STAGE-I; SURGERY; RESECTION;

D O I：

10.21037/jtd.2019.12.08

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Background: The present study was performed to investigate the perioperative dynamics of coagulation factor XIII (FXIII) in patients with non-small cell lung cancer undergoing video-assisted thoracoscopic surgery (VATS) lobectomy compared with open lobectomy. Methods: Perioperative coagulation factors including FXIII were analyzed in 30 patients who underwent VATS lobectomy and 10 patients who underwent open lobectomy at Teikyo University Hospital from December 2017 to April 2019. Results: Patients in the VATS lobectomy group showed higher FXIII activity on postoperative day (POD) 5 than patients in the open lobectomy group (P=0.028). The FXIII activity was significantly lower on POD3, POD5, and POD7 than that in the preoperative period and on POD1, even in patients who had undergone VATS lobectomy (P<0.001). No factors were found to affect the maintenance of FXIII in the VATS lobectomy group. Conclusion: The postoperative decrease of FXIII activity differed between patients who underwent VATS lobectomy and those who underwent open lobectomy. Based on the characteristics of FXIII, the FXIII activity may be a good marker of the invasiveness of VATS lobectomy versus open lobectomy.

引用

页码：5382 / 5389

页数：8

共 30 条

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