Hypertensive heart disease

被引：110
作者：
Diamond, JA
Phillips, RA
机构：
[1] Long Isl Jewish Med Ctr, Div Cardiol, New Hyde Pk, NY 10040 USA
[2] Albert Einstein Coll Med, New York, NY USA
[3] Lenox Hill Hosp, Dept Med, New York, NY 10021 USA
[4] NYU, Sch Med, New York, NY USA
来源：
HYPERTENSION RESEARCH | 2005年 / 28卷 / 03期
关键词：
left ventricular hypertrophy; left ventricular diastolic function; left ventricular mass; techniques; treatment;
D O I：
10.1291/hypres.28.191
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Left ventricular hypertrophy (LVH) and diastolic dysfunction (CHF-D) are the early manifestations of cardiovascular target organ damage in patients with arterial hypertension and signify hypertensive heart disease. Identification of hypertensive heart disease is critical, as these individuals are more prone to congestive heart failure, arrhythmias, myocardial infarction and sudden cardiac death. Regression of left ventricular (LV) mass with anti hypertensive therapy decreases the risk of future cardiovascular events. The goal of antihypertensive therapy is to both lower blood pressure (BP) and interrupt BP-independent pathophysiologic processes that promote LVH and CHF-D. The purpose of this review is to summarize current and emerging approaches to the pathophysiology and treatment of hypertensive heart disease.
引用
收藏
页码：191 / 202
页数：12
相关论文
共 100 条
  • [1] Transgenic mice with cardiac overexpression of alpha(1B)-adrenergic receptors - In vivo alpha(1)-adrenergic receptor-mediated regulation of beta-adrenergic signaling
    Akhter, SA
    Milano, CA
    Shotwell, KF
    Cho, MC
    Rockman, HA
    Lefkowitz, RJ
    Koch, WJ
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (34) : 21253 - 21259
  • [2] Left ventricle mass index and the common, functional, X-linked angiotensin II type-2 receptor gene polymorphism (-1332 G/A) in patients with systemic hypertension
    Alfakih, K
    Maqbool, A
    Sivananthan, M
    Walters, K
    Bainbridge, G
    Ridgway, J
    Balmforth, AJ
    Hall, AS
    [J]. HYPERTENSION, 2004, 43 (06) : 1189 - 1194
  • [3] *ALLHAT OFF COORD, 2002, JAMA-J AM MED ASSOC, V288, P2981, DOI DOI 10.1001/JAMA.288.23.2981
  • [4] Changes in early and late diastolic filling patterns induced by long-term adrenergic beta-blockade in patients with idiopathic dilated cardiomyopathy
    Andersson, B
    Caidahl, K
    diLenarda, A
    Warren, SE
    Goss, F
    Waldenstrom, A
    Persson, S
    Wallentin, I
    Hjalmarson, A
    Waagstein, F
    [J]. CIRCULATION, 1996, 94 (04) : 673 - 682
  • [5] Linkage of left ventricular contractility to chromosome 11 in humans - The HyperGEN study
    Arnett, DK
    Devereux, RB
    Kitzman, D
    Oberman, A
    Hopkins, P
    Atwood, L
    Dewan, A
    Rao, DC
    [J]. HYPERTENSION, 2001, 38 (04) : 767 - 772
  • [6] EFFECT OF ENALAPRIL ON CONGESTIVE-HEART-FAILURE TREATED WITH DIURETICS IN ELDERLY PATIENTS WITH PRIOR MYOCARDIAL-INFARCTION AND NORMAL LEFT-VENTRICULAR EJECTION FRACTION
    ARONOW, WS
    KRONZON, I
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1993, 71 (07) : 602 - 604
  • [7] ASYMPTOMATIC VENTRICULAR ARRHYTHMIAS AND MORTALITY RISK IN SUBJECTS WITH LEFT-VENTRICULAR HYPERTROPHY
    BIKKINA, M
    LARSON, MG
    LEVY, D
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1993, 22 (04) : 1111 - 1116
  • [8] LEFT-VENTRICULAR DIASTOLIC DYSFUNCTION AS A CAUSE OF CONGESTIVE-HEART-FAILURE - MECHANISMS AND MANAGEMENT
    BONOW, RO
    UDELSON, JE
    [J]. ANNALS OF INTERNAL MEDICINE, 1992, 117 (06) : 502 - 510
  • [9] Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease
    Brilla, CG
    Funck, RC
    Rupp, H
    [J]. CIRCULATION, 2000, 102 (12) : 1388 - 1393
  • [10] OUTCOME IN FAMILIAL SUBARACHNOID HEMORRHAGE
    BROMBERG, JEC
    RINKEL, GJE
    ALGRA, A
    LIMBURG, M
    VANGIJN, J
    [J]. STROKE, 1995, 26 (06) : 961 - 963
12345678910