Clinical study of the effectiveness of a dual amplified immunoassay (IDEIA PCE Chlamydia) for the diagnosis of male urethritis

被引：3

作者：

Hirose, T ^{[1
]}

Iwasawa, A ^{[1
]}

Satoh, T ^{[1
]}

Itoh, N ^{[1
]}

Tsukamoto, T ^{[1
]}

Gohro, T ^{[1
]}

Miyagishi, T ^{[1
]}

Ikegaki, S ^{[1
]}

Saka, T ^{[1
]}

Nishimura, M ^{[1
]}

Yamazaki, K ^{[1
]}

Hayashi, K ^{[1
]}

Yoshida, H ^{[1
]}

Hagiwara, T ^{[1
]}

机构：

[1] Sapporo Med Univ, Sch Med, Dept Urol, Chuo Ku, Sapporo, Hokkaido 060, Japan

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 1998年 / 9卷 / 07期

关键词：

Chlamydia trachomatis; IDEIA PCE Chlamydia; male urethritis; diagnosis;

D O I：

10.1258/0956462981922511

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A clinical study of patients with male urethritis (n=316) was undertaken to determine the sensitivity potential for a new dual amplified immunoassay (IDEIA. PCE Chlamydia(TM)). Increased sensitivity (98.8%, 84/85) was obtained for IDEIA PCE Chlamydia(TM) compared to a conventional antigen detection test (IDEIA Chlamydia(TM), 81.2%, 69/85) when testing urine samples. In a smaller patient population (n=104) the positivity rate for the first-void urine tested with IDEIA PCE Chlamydia(TM) of 30.8% (32/104) was similar to the 27.9% (29/104) obtained from urethral swabs tested with a DNA probe assay (PACE 2(TM)). The increased sensitivity of the test was confirmed with a commercial PCR kit (Amplicor(TM)) and nested PCR. The IDELA PCE Chlamydia(TM) kit has the sensitivity potential to be a clinically reliable alternative for detecting Chlamydia trachomatis.

引用

页码：414 / 417

页数：4

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