Clinical study of the effectiveness of a dual amplified immunoassay (IDEIA PCE Chlamydia) for the diagnosis of male urethritis

被引:3
作者
Hirose, T [1 ]
Iwasawa, A [1 ]
Satoh, T [1 ]
Itoh, N [1 ]
Tsukamoto, T [1 ]
Gohro, T [1 ]
Miyagishi, T [1 ]
Ikegaki, S [1 ]
Saka, T [1 ]
Nishimura, M [1 ]
Yamazaki, K [1 ]
Hayashi, K [1 ]
Yoshida, H [1 ]
Hagiwara, T [1 ]
机构
[1] Sapporo Med Univ, Sch Med, Dept Urol, Chuo Ku, Sapporo, Hokkaido 060, Japan
关键词
Chlamydia trachomatis; IDEIA PCE Chlamydia; male urethritis; diagnosis;
D O I
10.1258/0956462981922511
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A clinical study of patients with male urethritis (n=316) was undertaken to determine the sensitivity potential for a new dual amplified immunoassay (IDEIA. PCE Chlamydia(TM)). Increased sensitivity (98.8%, 84/85) was obtained for IDEIA PCE Chlamydia(TM) compared to a conventional antigen detection test (IDEIA Chlamydia(TM), 81.2%, 69/85) when testing urine samples. In a smaller patient population (n=104) the positivity rate for the first-void urine tested with IDEIA PCE Chlamydia(TM) of 30.8% (32/104) was similar to the 27.9% (29/104) obtained from urethral swabs tested with a DNA probe assay (PACE 2(TM)). The increased sensitivity of the test was confirmed with a commercial PCR kit (Amplicor(TM)) and nested PCR. The IDELA PCE Chlamydia(TM) kit has the sensitivity potential to be a clinically reliable alternative for detecting Chlamydia trachomatis.
引用
收藏
页码:414 / 417
页数:4
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