Inhalation of nitric oxide in the treatment of severe acute respiratory syndrome: A rescue trial in Beijing

被引:130
作者
Chen, LN
Liu, P
Gao, H
Sun, B
Chao, DS
Wang, F
Zhu, YJ
Hedenstierna, R
Wang, CG
机构
[1] Uppsala Univ, Dept Med Sci Clin Physiol, Uppsala, Sweden
[2] Capital Univ Med Sci, Beijing Chao Yang Hosp, Beijing, Peoples R China
[3] Beijing Inst Resp Med, Beijing, Peoples R China
[4] Beijing Union Med Coll Hosp, Dept Pulm Med, Beijing, Peoples R China
关键词
D O I
10.1086/425357
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Inhalation of nitric oxide (NO) improved arterial oxygenation and enabled the reduction of inspired oxygen therapy and airway pressure support in patients with severe acute respiratory syndrome (SARS). In addition, chest radiography showed decreased spread or density of lung infiltrates, and the physiological effects remained after termination of inhaled NO therapy. These findings suggest not only a pulmonary vasodilator effect of inhaled NO, but also an effect on SARS.
引用
收藏
页码:1531 / 1535
页数:5
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