Three new isopimaric acid diterpenoids from the bark of Cryptomeria japonica and their xanthine oxidase inhibitory activity

被引：2
|
作者：
Chang, Chi-, I [1 ,2 ]
Chen, Cheng-Chi [3 ]
Wang, Sheng-Yang [4 ,5 ]
Chen, Jih-Jung [6 ,7 ]
Chen, Chiy-Rong [8 ]
Chao, Che-Yi [9 ,10 ]
Kuo, Yueh-Hsiung [11 ,12 ,13 ]
机构：
[1] Natl Pingtung Univ Sci & Technol, Dept Biol Sci & Technol, Pingtung 912, Taiwan
[2] Natl Pingtung Univ Sci & Technol, Res Ctr Act Nat Prod Dev, Pingtung 912, Taiwan
[3] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan
[4] Natl Chung Hsing Univ, Dept Forestry, Taichung 402, Taiwan
[5] Acad Sinica, Agr Biotechnol Res Ctr, Taipei 115, Taiwan
[6] Natl Yang Ming Univ, Sch Pharmaceut Sci, Fac Pharm, Taipei 112, Taiwan
[7] China Med Univ Hosp, Dept Med Res, Taichung 404, Taiwan
[8] Natl Taitung Univ, Dept Life Sci, Taitung 950, Taiwan
[9] Asia Univ, Dept Food Nutr & Hlth Biotechnol, Taichung, Taiwan
[10] China Med Univ, China Med Univ Hosp, Dept Med Res, Taichung, Taiwan
[11] China Med Univ, Dept Chinese Pharmaceut Sci & Chinese Med Resourc, 91 Hsueh Shih Rd, Taichung 404, Taiwan
[12] Asia Univ, Dept Biotechnol, Taichung 413, Taiwan
[13] China Med Univ, Chinese Med Res Ctr, Taichung 404, Taiwan
来源：
PHYTOCHEMISTRY LETTERS | 2021年 / 46卷
关键词：
Cupressaceae; Cryptomeria japonica; Bark; Isopimarane; ABIETANE-TYPE DITERPENES; JAPANESE CEDAR; CONSTITUENTS; TERPENOIDS; EXTRACTS; QUINONE; OIL;
D O I：
10.1016/j.phytol.2021.09.005
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new isopimaric acid diterpenoids, 6-oxoisopimaric acid (1), 6 alpha-hydroxyisopimaric acid (2), and isopimara7,9(11),15-trien-18-oic acid (4), together with two known isopimaric acid diterpenoids, isopimaric acid (3), and 8(14),15-isopimaradien-18-oic acid (5), were isolated from the bark of Cryptomeria japonica D. Don. Their structures were determined by analysis of spectroscopic data and comparison with the spectral data of known analogues. At the concentration of 50 mu M, compounds 1-5 inhibited xanthine oxidase activity by 17.3, 16.5, 2.6, 30.5, and 24.5 %, respectively.
引用
收藏
页码：61 / 65
页数：5
相关论文
共 50 条
  • [21] THREE NEW DITERPENOIDS FROM THE BARK OF Ptychopetalum olacoides
    Tang, Wan-Xia
    Gong, Zi-Wei
    Zhao, Ming
    Wang, Qing-Bin
    Zhang, Wen-Zhi
    Zhang, Shu-Jun
    Fukuyama, Yoshiyasu
    CHEMISTRY OF NATURAL COMPOUNDS, 2018, 54 (04) : 701 - 704
  • [22] Three New Diterpenoids from the Bark of Ptychopetalum olacoides
    Wan-Xia Tang
    Zi-Wei Gong
    Ming Zhao
    Qing-Bin Wang
    Wen-Zhi Zhang
    Shu-Jun Zhang
    Yoshiyasu Fukuyama
    Chemistry of Natural Compounds, 2018, 54 : 701 - 704
  • [23] Three new sesquiterpenes from the black heartwood of Cryptomeria japonica
    Arihara, S
    Umeyama, A
    Bando, S
    Imoto, S
    Ono, M
    Yoshikawa, K
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2004, 52 (04) : 463 - 465
  • [24] Flavonoids from Cyclopia genistoides and Their Xanthine Oxidase Inhibitory Activity
    Roza, Orsolya
    Martins, Ana
    Hohmann, Judit
    Lai, Wan-Chun
    Eloff, Jacobus
    Chang, Fang-Rong
    Csupor, Dezso
    PLANTA MEDICA, 2016, 82 (14) : 1274 - 1278
  • [25] Xanthine oxidase inhibitory activity of compounds from Chythrantus claneianus
    Gojayev, Anar Sahib
    Bankeu, Jean Jules Kezetas
    Awantu, Angelbert Fusi
    Nkanwen, Eric Rene Sieliatchom
    Ali, Muhammad Shaiq
    Lenta, Bruno Ndjakou
    Guliyev, Akif Alakbar
    Noungoue, Diderot Tchamo
    Ngouela, Silvere Augustin
    Tsamo, Etienne
    BANGLADESH JOURNAL OF PHARMACOLOGY, 2013, 8 (01) : 78 - 83
  • [26] New prenylflavonol glycosides with xanthine oxidase inhibitory activity from the leaves of Cyclocarya paliurus
    Ye, Zi-Jun
    He, Xiao-Ai
    Wu, Jian-Ping
    Li, Jing
    Chang, Xi-Wen
    Tan, Jie
    Lv, Wen-Yan
    Zhu, Hui
    Sun, Hui-Hui
    Wang, Wen-Xuan
    Chen, Zu-Hui
    Zhu, Gang-Zhi
    Xu, Kang-Ping
    BIOORGANIC CHEMISTRY, 2020, 101
  • [27] Xanthine oxidase inhibitory activity of isoflavonoids from Apios americana
    Kim, Jang Hoon
    Jin, Chang Hyun
    COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 83
  • [28] Screening of plants from New Caledonia and Vanuatu for inhibitory activity of xanthine oxidase and elastase
    Bosisio, E
    Mascetti, D
    Cabalion, P
    PHARMACEUTICAL BIOLOGY, 2000, 38 (01) : 18 - 24
  • [29] Polyphenols from Cyclopia genistoides and their xanthine oxidase inhibitory activity
    Roza, O.
    Martins, A.
    Hohmann, J.
    Lai, W. C.
    Chang, F. R.
    Eloff, J.
    Csupor, D.
    PLANTA MEDICA, 2015, 81 (16) : 1464 - 1464
  • [30] Identification of Components from Acetobacter pasteurianus and their Xanthine Oxidase Inhibitory Activity
    Ming-Der Wu
    Ming-Jen Cheng
    Yen-Lin Chen
    Mei-Huei Chen
    Siao-Jhen Chen
    Li-Wen Yu
    Hsun-Yin Hsu
    Chemistry of Natural Compounds, 2020, 56 : 1135 - 1136
12345