Carbon Nanotubes: Current Perspectives on Diverse Applications in Targeted Drug Delivery and Therapies

被引:49
作者
Rahamathulla, Mohamed [1 ]
Bhosale, Rohit R. [2 ]
Osmani, Riyaz A. M. [3 ]
Mahima, Kasturi C. [3 ]
Johnson, Asha P. [3 ]
Hani, Umme [1 ]
Ghazwani, Mohammed [1 ]
Begum, Mohammed Y. [1 ]
Alshehri, Sultan [4 ]
Ghoneim, Mohammed M. [5 ]
Shakeel, Faiyaz [4 ]
Gangadharappa, Hosahalli V. [3 ]
机构
[1] King Khalid Univ, Dept Pharmaceut, Coll Pharm, Abha 61421, Saudi Arabia
[2] Deemed Univ, Krishna Inst Med Sci, Krishna Inst Pharm, Dept Pharmaceut, Karad 415539, Maharashtra, India
[3] JSS Acad Higher Educ & Res, Dept Pharmaceut, JSS Coll Pharm, Mysuru 570015, Karnataka, India
[4] King Saud Univ, Dept Pharmaceut, Coll Pharm, Riyadh 11451, Saudi Arabia
[5] AlMaarefa Univ, Dept Pharm Practice, Coll Pharm, Ad Diriyah 13713, Saudi Arabia
关键词
carbon nanotubes; toxicity; targeted drug delivery; therapies; biomedical applications; patents; IN-VITRO; CANCER-CHEMOTHERAPY; TOXICITY EVALUATION; CELLULAR UPTAKE; BRAIN; NANOPARTICLES; TRANSPORTERS; DOXORUBICIN; REDUCTION; CHARGE;
D O I
10.3390/ma14216707
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Current discoveries as well as research findings on various types of carbon nanostructures have inspired research into their utilization in a number of fields. These carbon nanostructures offer uses in pharmacy, medicine and different therapies. One such unique carbon nanostructure includes carbon nanotubes (CNTs), which are one-dimensional allotropes of carbon nanostructure that can have a length-to-diameter ratio greater than 1,000,000. After their discovery, CNTs have drawn extensive research attention due to their excellent material properties. Their physical, chemical and electronic properties are excellent and their composites provide great possibilities for enormous nanometer applications. The current study provides a systematic review based on prior literature review and data gathered from various sources. The various research studies from many research labs and organizations were systematically retrieved, collected, compiled and written. The entire collection and compilation of this review concluded the use of CNT approaches and their efficacy and safety for the treatment of various diseases such as brain tumors or cancer via nanotechnology-based drug delivery, phototherapy, gene therapy, antiviral therapy, antifungal therapy, antibacterial therapy and other biomedical applications. The current review covers diverse applications of CNTs in designing a range of targeted drug delivery systems and application for various therapies. It concludes with a discussion on how CNTs based medicines can expand in the future.
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页数:29
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