Effect of Apomorphine on Non-Motor Symptoms in Parkinson's Disease

被引：1
作者：
Honig, H. [1 ]
Odin, P. [1 ,2 ]
Chaudhuri, K. R. [3 ]
机构：
[1] Klinikum Bremerhaven, Abt Neurol, D-27574 Bremerhaven, Germany
[2] Univ Krankenhaus, Abt Neurol, Lund, Sweden
[3] Kings Coll London, Dept Neurol, NPF Ctr Excellence, London WC2R 2LS, England
来源：
AKTUELLE NEUROLOGIE | 2011年 / 38卷
关键词：
Parkinson; pump; apomorphine; infusion; non-motor; SUBCUTANEOUS APOMORPHINE; DOPAMINERGIC MODULATION; MULTICENTER; PRAMIPEXOLE; LEVODOPA; DEPRESSION; INFUSION; APATHY; STIMULATION; DIAGNOSIS;
D O I：
10.1055/s-0030-1265982
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
In Parkinson's disease non-motor symptoms can appear even before the motor symptoms. Additionally to motor fluctuations and dyskinesias, the non-motor symptoms constitute one of the main problems when treating Parkinson's disease. They are also of high relevance for the quality of life. There are indications that a continuous dopaminergic stimulation can improve symptoms such as depression, sleep as well as autonomic disturbances. Treatment with apomorphine infusion subcutaneously or Duodopa (L-dopa/carbidopa) intraduodenally with portable pump systems are well-established regarding management of motor fluctuations and dyskinesias. Regarding effects on non-motor symptoms there are so far only a few studies with limited number of cases available.
引用
收藏
页码：S34 / S38
页数：5
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