Synthesis of new L-ascorbic ferulic acid hybrids

被引：21

作者：

Voisin-Chiret, Anne Sophie ^{[1
]}

Bazin, Marc-Antoine ^{[1
]}

Lancelot, Jean-Charles ^{[1
]}

Rault, Sylvain ^{[1
]}

机构：

[1] Univ Caen, UFR Sci Pharmaceut, Ctr Etud Rech Med Normandie, UPRES EA 3915, F-14032 Caen, France

来源：

MOLECULES | 2007年 / 12卷 / 11期

关键词：

ascorbic acid; ferulic acid; hybridization; antioxidant; oxidative stress;

D O I：

10.3390/12112533

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A feasibility and chemical study of the coupling conditions of L-ascorbic acid with ferulic acid derivatives are described on the basis of the known synergistic effects of mixtures of various antioxidants. Novel L-ascorbic ferulic hybrids linked at the C-3 hydroxyl group were prepared with the aim to protect the alcohol function and the enediol system.

引用

页码：2533 / 2545

页数：13

共 23 条

[1] Stability of vitamin C derivatives in solution and topical formulations
Austria, R
Semenzato, A
Bettero, A
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1997, 15 (06) : 795 - 801
[2] Original one-pot microwave-promoted Hunsdiecker-Suzuki strategy:: straightforward access to trans-1,2-diarylethenes from cinnamic acids
Bazin, Marc-Antoine
El Kihel, Laiela
Lancelot, Jean-Charles
Rault, Sylvain
[J]. TETRAHEDRON LETTERS, 2007, 48 (25) : 4347 - 4351
[3] BOTTCHER A, 2000, Patent No. 006121464
[4] BOWEN PE, 1995, AM J CLIN NUTR, V62, P1403
[5] Topical vitamin C in aging
Colven, RM
Pinnell, SR
[J]. CLINICS IN DERMATOLOGY, 1996, 14 (02) : 227 - 234
[6] COMPARISON OF THE ANTIOXIDATIVE ACTIVITY OF SOME ACID-PHENOLS - STRUCTURE ACTIVITY RELATIONSHIP
CUVELIER, ME
RICHARD, H
BERSET, C
[J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1992, 56 (02) : 324 - 325
[7] Galey J.-B.Terranova, 1995, [No title captured], Patent No. [EP664290A1, 664290]
[8] GARCIAMERCIER C, 1999 2000 M AAD EADV
[9] HALLIWELL B, 1993, AM J CLIN NUTR, V57, P715
[10] TOTAL SYNTHESIS OF (R)-GLYCEROL ACETONIDE AND THE ANTIEPILEPTIC AND HYPOTENSIVE DRUG "(-)-GAMMA-AMINO-BETA-HYDROXYBUTYRIC ACID (GABOB) - USE OF VITAMIN-C AS A CHIRAL STARTING MATERIAL
JUNG, ME
SHAW, TJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (20) : 6304 - 6311

← 1 2 3 →