Coding repeats and evolutionary "agility"

被引：32
作者：
Caburet, S
Cocquet, J
Vaiman, D
Veitia, RA
机构：
[1] INSERM, U709, F-75014 Paris, France
[2] Univ Paris 05, F-75270 Paris, France
来源：
BIOESSAYS | 2005年 / 27卷 / 06期
关键词：
D O I：
10.1002/bies.20248
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The rapid generation of new shapes observed in the living world is the result of genetic variation, especially in "morphological" developmental genes. Many of these genes contain coding tandem repeats. Fondon and Garner have shown that expansions and contractions of these repeats are associated with the great diversity of morphologies observed in the domestic dog, Canis familiaris.((1)) In particular, they found that the repeat variations in two genes were significantly associated with changes in limb and skull morphology. These results open the possibility that such a mechanism contributes to the diversity of life. (c) 2005 Wiley Periodicals, Inc.
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页码：581 / 587
页数：7
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