Novel analogues of 3-substituted-2,3-dihydro-1,4-dioxino[2,3-b]pyridines:: modifications in the dioxane ring

被引：5

作者：

Bartoloméa, JM

Alcázar, J

Andrés, JI

De Bruyn, M

Fernández, J

Matesanz, E

Van Emelen, K

机构：

[1] Johnson & Johnson Pharmaceut Res & Dev, Div Janssen Cilag SA, Dept Med Chem, Toledo 45007, Spain

[2] Johnson & Johnson Pharmaceut Res & Dev, Div Janssen Pharmaceut NV, Dept Med Chem, B-2340 Beerse, Belgium

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 47期

关键词：

D O I：

10.1016/j.tetlet.2003.09.145

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of a series of novel analogues of the 3-substituted-2,3-dihydro-1,4-dioxino[2,3-b]pyridine core, modified in the non-aromatic ring, is described. Due to the presence of a versatile hydroxymethyl group in their structure, these novel scaffolds are attractive intermediates for the preparation of potential new therapeutic agents. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：8545 / 8548

页数：4

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