The role of β-tubulin isotypes in resistance to antimitotic drugs

被引:78
作者
Burkhart, CA
Kavallaris, M
Horwitz, SB
机构
[1] Yeshiva Univ Albert Einstein Coll Med, Dept Mol Pharmacol, Bronx, NY 10461 USA
[2] Childrens Canc Inst Australia Med Res, Randwick, NSW 2031, Australia
来源
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER | 2001年 / 1471卷 / 02期
关键词
beta-tubulin isotype; antimitotic agent; taxol; Vinca alkaloid; resistance;
D O I
10.1016/S0304-419X(00)00022-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:O1 / O9
页数:9
相关论文
共 63 条
[1]  
BANERJEE A, 1992, J BIOL CHEM, V267, P5625
[2]  
BANERJEE A, 1990, J BIOL CHEM, V265, P1794
[3]  
BANERJEE A, 1988, J BIOL CHEM, V263, P3029
[4]  
BANERJEE A, 1992, J BIOL CHEM, V267, P13335
[5]   MECHANISMS OF REGULATING TUBULIN SYNTHESIS IN CULTURED MAMMALIAN-CELLS [J].
BENZEEV, A ;
FARMER, SR ;
PENMAN, S .
CELL, 1979, 17 (02) :319-325
[6]  
Blade K, 1999, J CELL SCI, V112, P2213
[7]   A CHICKEN-YEAST CHIMERIC BETA-TUBULIN PROTEIN IS INCORPORATED INTO MOUSE MICROTUBULES INVIVO [J].
BOND, JF ;
FRIDOVICHKEIL, JL ;
PILLUS, L ;
MULLIGAN, RC ;
SOLOMON, F .
CELL, 1986, 44 (03) :461-468
[8]  
BURKHART CA, 1998, THESIS TAXOL MECH AC, P151
[9]   ANALYSIS OF BETA-TUBULIN SEQUENCES REVEALS HIGHLY CONSERVED, COORDINATED AMINO-ACID SUBSTITUTIONS - EVIDENCE THAT THESE HOT-SPOTS ARE DIRECTLY INVOLVED IN THE CONFORMATIONAL CHANGE REQUIRED FOR DYNAMIC INSTABILITY [J].
BURNS, RG ;
SURRIDGE, C .
FEBS LETTERS, 1990, 271 (1-2) :1-8
[10]   RESISTANCE TO ANTIMITOTIC AGENTS AS GENETIC PROBES OF MICROTUBULE STRUCTURE AND FUNCTION [J].
CABRAL, F ;
BARLOW, SB .
PHARMACOLOGY & THERAPEUTICS, 1991, 52 (02) :159-171