Bone mineral density after total joint arthroplasty of lower extremities in rheumatoid arthritis patients

被引：1

作者：

Miyamoto, S ^{[1
]}

Kageyama, Y ^{[1
]}

Ozeki, T ^{[1
]}

Suzuki, M ^{[1
]}

Ichikawa, T ^{[1
]}

Inoue, T ^{[1
]}

机构：

[1] Hamamatsu Univ Sch Med, Dept Orthoped, Hamamatsu, Shizuoka 43131, Japan

来源：

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY | 2001年 / 121卷 / 03期

关键词：

rheumatoid arthritis; dual-energy X-ray absorptiometry; total joint arthroplasty; bone mineral density;

D O I：

10.1007/s004020000196

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We studied the effects on the axial bone mass of total joint arthroplasty (TJA) for lower extremities in 48 female rheumatoid arthritis (RA) patients by using dual-energy X-ray absorptiometry (DXA). Twenty-nine postmenopausal RA patients treated only with nonsteroidal anti-inflammatory drugs (NSAIDs) served as controls. They were studied for an average duration of 63 months. The reduction in the bone mineral density (BMD) of the lumbar spine (L2-4) was significant in both groups (p < 0.01<similar to>0.05), but it was not statistically different between the two groups. The BMD of the femoral neck decreased significantly in both groups (p < 0.01-0.05) after 2 years, but it was not statistically different between the two groups. Our data suggest that TJA slowed the rapid axial bone loss usually associated with advanced RA.

引用

页码：127 / 130

页数：4

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