Novel and highly regioselective approach to 5-methoxy-6-substituted-3-sulfonyl-δ-enlactams from 5-methoxy-3-sulfonyl glutarimide:: Synthesis of cis-2-substituted-3-piperidinols

被引：20

作者：

Tsai, MR ^{[1
]}

Chen, BF ^{[1
]}

Cheng, CC ^{[1
]}

Chang, NC ^{[1
]}

机构：

[1] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 804, Taiwan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 05期

关键词：

D O I：

10.1021/jo048073e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A convenient method for the preparation of 5-methoxy-6-substituted-3-sulfonyl-delta-enlactams via regioselective nucleophilic addition to 5-methoxy-3-sulfonyl glutarimide is described. Formal syntheses of L-733,060, CP-99,994, and cassine are also reported.

引用

页码：1780 / 1785

页数：6

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