Bioaccumulation and oxidative stress responses measured in the estuarine ragworm (Nereis diversicolor) exposed to dissolved, nano- and bulk-sized silver

被引：46

作者：

Cozzari, Margherita ^{[1
]}

Elia, Antonia Concetta ^{[1
]}

Pacini, Nicole ^{[1
]}

Smith, Brian D. ^{[2
]}

Boyle, David ^{[3
]}

Rainbow, Philip S. ^{[2
]}

Khan, Farhan R. ^{[2
,4
]}

机构：

[1] Univ Perugia, Dept Chem Biol & Biotechnol, I-06123 Perugia, Italy

[2] Nat Hist Museum, Dept Life Sci, London SW7 5BD, England

[3] Univ Plymouth, Sch Biomed & Biol Sci, Ecotoxicol Res & Innovat Ctr, Plymouth PL4 8AA, Devon, England

[4] Roskilde Univ, Dept Environm Social & Spatial Change ENSPAC, DK-4000 Roskilde, Denmark

来源：

ENVIRONMENTAL POLLUTION | 2015年 / 198卷

关键词：

Ag NPs; Biomarkers; Oxidative stress; Sediment exposure; CLAM SCROBICULARIA-PLANA; ANTIOXIDANT RESPONSES; IN-VIVO; NANOPARTICLES; TOXICITY; GLUTATHIONE; SEDIMENT; ENZYMES; METALS; POLYCHAETE;

D O I：

10.1016/j.envpol.2014.12.015

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The impact of Ag NPs on sediment-dwelling organisms has received relatively little attention, particularly in linking bioaccumulation to oxidative injury. The polychaete Nereis diversicolor was exposed to sediments spiked with dissolved Ag (added as AgNO3), Ag NPs (63 +/- 27 nm) and larger bulk Ag particles (202 +/- 56 mu m), for up to 11 days at sublethal concentrations (nominally 2.5, 5, 10 i.tg Ag g1 sediment (dw)). There were concentration- and time-dependent differences in the accumulation of the three Ag forms, but all three forms elicited an oxidative stress response. In the cases of Ag NPs and bulk Ag particles, changes in antioxidant markers (glutathione, SOD, CAT, GPx, SeGPx, GST and GR) occurred without significant Ag accumulation. Differences in biomarker profiles between the three Ag forms suggest that the mechanism of oxidative stress caused by particulate Ag is distinct from that of dissolved Ag. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：32 / 40

页数：9