New candidate markers of phosphorus status in beef breeder cows

被引:25
作者
Anderson, S. T. [1 ]
Kidd, L. J. [2 ]
Benvenutti, M. A. [3 ,6 ]
Fletcher, M. T. [4 ]
Dixon, R. M. [5 ]
机构
[1] Univ Queensland, Sch Biomed Sci, Lab Anim Endocrinol, Fac Med, St Lucia, Qld 4072, Australia
[2] Univ Queensland, Sch Vet Sci, Gatton, Qld 4343, Australia
[3] Univ Queensland, Ctr Anim Sci, QAAFI, POB 6014, Gayndah, Qld 4625, Australia
[4] Univ Queensland, Ctr Anim Sci, QAAFI, POB 156, Archerfield Bc, Qld 4108, Australia
[5] Univ Queensland, Ctr Anim Sci, QAAFI, POB 6014, Rockhampton, Qld 4702, Australia
[6] Dept Agr & Fisheries, Gatton, Qld 4343, Australia
关键词
bone alkaline phosphatase; bone mobilisation; CTX-1; lactation; ALKALINE-PHOSPHATASE ACTIVITY; PERIPARTURIENT DAIRY-COWS; HORMONE-RELATED PROTEIN; VITAMIN-D METABOLISM; BONE METABOLISM; DIETARY PHOSPHORUS; PARATHYROID-HORMONE; INORGANIC PHOSPHORUS; EARLY LACTATION; MILK FEVER;
D O I
10.1071/AN17363
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Determining the phosphorus (P) status of cattle grazing P-deficient rangelands in northern Australia is important for improving animal production in these areas. Plasma inorganic P concentration is currently the best diagnostic marker of dietary P deficiency in growing cattle but is not suitable for assessing the P status of breeder cows, which often mobilise substantial bone and soft tissue reserves in late pregnancy and lactation. Markers of bone turnover offer potential as markers of P status in cattle, as they reflect bone mobilisation or bone formation. Recent experiments investigating the physiology of beef breeder cows during diet P deficiency have indicated that the ratio of plasma total calcium concentration to plasma inorganic P concentration might be suitable as a simple index of P deficiency. However, a more specific measure of increased bone mobilisation in P-deficient breeders is plasma concentration of C-terminal telopeptide of Type 1 collagen. Also, plasma concentration of bone alkaline phosphatase is a marker of defective bone mineralisation in dietary P deficiency. These candidate markers warrant further investigation to determine their predictive value for P deficiency in cattle.
引用
收藏
页码:2291 / 2303
页数:13
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