Halogenated Natural Products in Dolphins: Brain-Blubber Distribution and Comparison with Halogenated Flame Retardants

被引：32

作者：

Baron, E. ^{[1
]}

Hauler, C. ^{[2
]}

Gallistl, C. ^{[2
]}

Gimenez, J. ^{[3
]}

Gauffier, P. ^{[4
]}

Castillo, J. J. ^{[5
]}

Fernandez-Maldonado, C. ^{[6
]}

de Stephanis, R. ^{[4
]}

Vetter, W. ^{[2
]}

Eljarrat, E. ^{[1
]}

Barcelo, D. ^{[1
]}

机构：

[1] Spanish Council Sci Res CSIC, Inst Environm Assessment & Water Res Studies IDAE, Barcelona 08034, Spain

[2] Univ Hohenheim, Inst Food Chem, D-70599 Stuttgart, Germany

[3] CSIC, Estn Biol Donana, Dept Conservat Biol, Seville 42092, Spain

[4] Conservat Informat & Res Cetaceans CIRCE, Cadiz 11390, Spain

[5] CREMA, Malaga 29004, Spain

[6] Junta Andalucia, Consejeria Medio Ambiente & Ordenac Terr, Agencia Medio Ambiente & Agua Andalucia, Seville 41092, Spain

来源：

ENVIRONMENTAL SCIENCE & TECHNOLOGY | 2015年 / 49卷 / 15期

关键词：

POLYBROMINATED DIPHENYL ETHERS; PERSISTENT ORGANIC POLLUTANTS; MASS-SPECTROMETRY METHOD; DECHLORANE PLUS; MARINE BIOTA; TISSUE DISTRIBUTION; TURSIOPS-TRUNCATUS; POLYCHLORINATED-BIPHENYLS; ORGANOBROMINE COMPOUNDS; ORGANOHALOGEN COMPOUNDS;

D O I：

10.1021/acs.est.5b02736

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Halogenated natural products (MHC-1, TriBHD, TetraBHD, Me0-PBDEs, Ql, and related PMBPs) and halogenated flame retardants (PBDEs, HBB, Dec 602, Dec 603, and DP) in blubber and brain are reported from five Alboran Sea delphinids (Spain). Both HNPs and HFRs were detected in brain, implying that they are able to surpass the blood-brain barrier and reach the brain, which represents a new finding for some compounds, such as Q1 and PMBPs, MHC-1, TriBHD, TetraBHD, or Dec 603. Moreover, some compounds (TetraBHD, BDE-153, or HBB) presented higher levels in brain than in blubber. This study evidence the high concentrations of HNPs in the marine environrnent, especially in top predators. It shows the importance of further monitoring these natural compounds and evaluating their potential toxicity, when most studies focus on anthropogenic compounds only. While no bioaccumulation was found for Sigma HNPs, Sigma HFRs increased significantly with body size for both common and striped dolphins. Studies evaluating BBB permeation mechanisms of these compounds together with their potential neurotoxic effects in dolphins are recommended.

引用

页码：9073 / 9083

页数：11

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