Risk of pneumonia in patients with insomnia: A nationwide population-based retrospective cohort study

被引：9
作者：
Lin, Chia-Ling [1 ]
Liu, Ta-Chun [2 ]
Chung, Chi-Hsiang [3 ]
Chien, Wu-Chien [4 ,5 ,6 ,7 ]
机构：
[1] Chang Gung Univ Sci & Technol, Dept Nursing, Taoyuan, Taiwan
[2] Univ Southern Calif, Keck Sch Med, Dept Stem Cell Biol & Regenerat Med, Los Angeles, CA 90033 USA
[3] Taiwanese Injury Prevent & Safety Promot Assoc, Taipei, Taiwan
[4] Triserv Gen Hosp, Dept Med Res, Taipei, Taiwan
[5] Natl Def Med Ctr, Taipei, Taiwan
[6] Natl Def Med Ctr, Sch Publ Hlth, Taipei, Taiwan
[7] 161,Sec 6,Ming Chuang E Rd, Taipei 114, Taiwan
来源：
JOURNAL OF INFECTION AND PUBLIC HEALTH | 2018年 / 11卷 / 02期
关键词：
Insomnia; Pneumonia; Retrospective cohort study; Infectious disease; REDUCES NATURAL-KILLER; SHORT-SLEEP DURATION; C-REACTIVE PROTEIN; ANTIBODY-RESPONSE; LEPTIN LEVELS; COMMON COLD; DEPRIVATION; VACCINATION; SUSCEPTIBILITY; HUMANS;
D O I：
10.1016/j.jiph.2017.08.002
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Evidence is lacking regarding whether insomnia increases the risk of infectious disease. Accordingly, the present study examined the risk of pneumonia in patients with insomnia. This study was a population-based retrospective cohort study on a cohort of 8061 patients with insomnia and a control cohort of 16,112 patients (matched by age, sex, and year of diagnosis) from the Taiwan National Health Insurance Research Database for the 2000-2010 period. Overall incidence of pneumonia was 50.6 per 1000 person-years in the insomnia cohort, which was significantly higher than that in the control cohort (30.9 per 1000 person-years). Overall, the insomnia cohort exhibited a higher risk of pneumonia (HR=2.43; CI, 2.24-2.62). By age group, the risk of pneumonia was significantly higher in the insomnia cohort for those aged <= 40 years (HR=3.23, CI: 1.38-7.57), 41-65 years (HR=2.62, CI: 2.07-3.32), and >65years (CI: 2.21-2.61). Compared with the controls, the insomnia cohort exhibited a higher risk of pneumonia, particularly in young adults. (C) 2017 The Authors. Published by Elsevier Limited on behalf of King Saud Bin Abdulaziz University for Health Sciences.
引用
收藏
页码：270 / 274
页数：5
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