The use of cardiovascular magnetic resonance as an early non-invasive biomarker for cardiotoxicity in cardio-oncology

被引:15
作者
Burrage, Matthew K. [1 ]
Ferreira, Vanessa M. [1 ]
机构
[1] Univ Oxford, Oxford Ctr Clin Magnet Resonance Res OCMR, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England
关键词
Cardiovascular magnetic resonance (CMR); cardio-oncology; cardiotoxicity; BREAST-CANCER PATIENTS; EMISSION COMPUTED-TOMOGRAPHY; DIFFUSE MYOCARDIAL FIBROSIS; GLOBAL LONGITUDINAL STRAIN; ISCHEMIC-HEART-DISEASE; EJECTION FRACTION; ANTHRACYCLINE CARDIOTOXICITY; CONSTRICTIVE PERICARDITIS; PERFUSION; ECHOCARDIOGRAPHY;
D O I
10.21037/cdt-20-165
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Contemporary cancer therapy has resulted in significant survival gains for patients. However, many current and emerging cancer therapies have an associated risk of cardiotoxicity, either acutely or later in life. Regular cardiac screening and surveillance is recommended for patients undergoing treatment for cancer, with emphasis on the early detection of cardiotoxicity before irreversible complications develop. Cardiovascular magnetic resonance imaging is able to accurately assess cardiac structure, function, and perform advanced myocardial tissue characterisation, including perfusion, features which may facilitate the diagnosis and management of cardiotoxicity in cancer survivors. This review outlines the current standards for the diagnosis and screening of cardiotoxicity, with particular focus on current and future applications of cardiovascular magnetic resonance imaging.
引用
收藏
页码:610 / 624
页数:15
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