Palladium-Catalyzed Hydrodefluorination of Fluoroarenes

被引：0
作者：
Gair, Joseph J. [1 ]
Grey, Ronald L. [1 ]
Giroux, Simon [1 ]
Brodney, Michael A. [1 ]
机构：
[1] Vertex Pharmaceut Inc, 50 Northern Ave, Boston, MA 02210 USA
来源：
ORGANIC SYNTHESES | 2021年 / 98卷
关键词：
F BOND ACTIVATION; NUCLEOPHILIC AROMATIC-SUBSTITUTION; C-F; HYDROGEN-TRANSFER; ELECTROCHEMICAL HYDRODEFLUORINATION; FACILE ACCESS; ARYL HALIDES; FLUORINE; HYDRODEHALOGENATION; NHC;
D O I：
10.15227/orgsyn.098.0131
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：131 / +
页数：19
相关论文
共 51 条
[1]   Metal-mediated reductive hydrodehalogenation of organic halides [J].
Alonso, F ;
Beletskaya, IP ;
Yus, M .
CHEMICAL REVIEWS, 2002, 102 (11) :4009-4091
[2]   C-F Bond Activation in Organic Synthesis [J].
Amii, Hideki ;
Uneyama, Kenji .
CHEMICAL REVIEWS, 2009, 109 (05) :2119-2183
[3]   Hydrogenolysis of aryl halides by hydrogen gas and hydrogen transfer over palladium-supported catalysts [J].
Aramendia, MA ;
Borau, V ;
Carcía, IM ;
Jiménez, C ;
Marinas, A ;
Marinas, JM ;
Urbano, FJ .
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE II FASCICULE C-CHIMIE, 2000, 3 (06) :465-470
[4]   Mechanism of the Catalytic Hydrodefluorination of Pentafluoropyridine by Group Six Triangular Cluster Hydrides Containing Phosphines: A Combined Experimental and Theoretical Study [J].
Beltran, Tomas F. ;
Feliz, Marta ;
Llusar, Rosa ;
Mata, Jose A. ;
Safont, Vicent S. .
ORGANOMETALLICS, 2011, 30 (02) :290-297
[5]   Fluorine in medicinal chemistry [J].
Böhm, HJ ;
Banner, D ;
Bendels, S ;
Kansy, M ;
Kuhn, B ;
Müller, K ;
Obst-Sander, U ;
Stahl, M .
CHEMBIOCHEM, 2004, 5 (05) :637-643
[6]   Pd/C-catalyzed room-temperature hydrodehalogenation of aryl halides with hydrazine hydrochloride [J].
Cellier, PP ;
Spindler, JF ;
Taillefer, M ;
Cristau, HJ .
TETRAHEDRON LETTERS, 2003, 44 (38) :7191-7195
[7]   Rhodium-Catalyzed ortho-Selective C-F Activation and Hydrodefluorination of Heterocycle-Substituted Polyfluoroarenes: Dominated by Phosphine Ligands [J].
Chen, Jianping ;
Huang, Dongyang ;
Ding, Yuqiang .
CHEMISTRYSELECT, 2017, 2 (03) :1219-1224
[8]   Palladium-Catalyzed Ortho-Selective C-F Activation of Polyfluoroarenes with Triethylsilane: A Facile Access to Partially Fluorinated Aromatics [J].
Chen, Zhao ;
He, Chun-Yang ;
Yin, Zengsheng ;
Chen, Liye ;
He, Yi ;
Zhang, Xingang .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (22) :5813-5817
[9]  
Cybulski M. K, 2017, ANGEW CHEM, V129, P1537
[10]   C-F Bond Activation of P(C6F5)3 by Ruthenium Dihydride Complexes: Isolation and Reactivity of the "Missing" Ru(PPh3)3H(halide) Complex, Ru(PPh3)3HF [J].
Cybulski, Mateusz K. ;
Davies, Caroline J. E. ;
Lowe, John P. ;
Mahon, Mary F. ;
Whittlesey, Michael K. .
INORGANIC CHEMISTRY, 2018, 57 (21) :13749-13760
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