A Self-restricted CRISPR System to Reduce Off-target Effects

被引：63

作者：

Chen, Yanhao ^{[1
,2
]}

Liu, Xiaojian ^{[1
,2
]}

Zhang, Yongxian ^{[1
,2
]}

Wang, Hui ^{[2
,3
]}

Ying, Hao ^{[2
,3
]}

Liu, Mingyao ^{[4
,5
]}

Li, Dali ^{[4
,5
]}

Lui, Kathy O. ^{[6
,7
]}

Ding, Qiurong ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Biol Sci, CAS Key Lab Nutr & Metab, Inst Nutr Sci, Shanghai, Peoples R China

[2] Univ Chinese Acad Sci, Shanghai, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Biol Sci, CAS Key Lab Food Safety Res, Inst Nutr Sci, Shanghai, Peoples R China

[4] East China Normal Univ, Shanghai Key Lab Regulatory Biol, Inst Biomed Sci, Shanghai, Peoples R China

[5] East China Normal Univ, Sch Life Sci, Shanghai, Peoples R China

[6] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Chem Pathol, Shatin, Hong Kong, Peoples R China

[7] Chinese Univ Hong Kong, Prince Wales Hosp, Li Ka Shing Inst Hlth Sci, Shatin, Hong Kong, Peoples R China

来源：

MOLECULAR THERAPY | 2016年 / 24卷 / 09期

关键词：

CAS9; NUCLEASES; DELIVERY;

D O I：

10.1038/mt.2016.172

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：1508 / 1510

页数：3

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