Towards the asymmetric synthesis of bryostatin 1

被引：17

作者：

DeBrabander, J

Vandewalle, M

机构：

[1] University of Gent, Department of Organic Chemistry, Laboratory for Organic Synthesis, B-9000 Gent, Krijgslaan

来源：

PURE AND APPLIED CHEMISTRY | 1996年 / 68卷 / 03期

关键词：

D O I：

10.1351/pac199668030715

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The construction of the fragments C-1-C-9 3 and C-17-C-27 4a of the bryostatins in a enantioselective and highly diastereoselective fashion is described, The usefulness of the ''chiron'' approach is illustrated with the synthesis of these fragments from respectively D-pantolactone (6) and D-isobutyl lactate (14) as chiral templates.

引用

页码：715 / 718

页数：4

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