Liver Retransplantation in Patients With Acquired Familial Amyloid Polyneuropathy: A Portuguese Center Experience

被引：7

作者：

Vieira, H. ^{[1
,2
]}

Rodrigues, C. ^{[1
]}

Pereira, L. ^{[1
,2
]}

Jesus, J. ^{[1
]}

Bento, C. ^{[1
,2
]}

Seco, C. ^{[1
,2
]}

Pinto, F. ^{[1
,2
]}

Eufrasio, A. ^{[1
,2
]}

Calretas, S. ^{[2
]}

Silva, N. ^{[2
]}

Ferrao, J. ^{[2
]}

Tome, L. ^{[2
]}

Barros, A. ^{[2
]}

Diogo, D. ^{[2
]}

Furtado, E. ^{[2
]}

机构：

[1] Ctr Hosp & Univ Coimbra, Anesthesiol Serv, P-3000075 Coimbra, Portugal

[2] Ctr Hosp & Univ Coimbra, Unidade Transplantacao Hepat Pediat & Adultos, P-3000075 Coimbra, Portugal

来源：

TRANSPLANTATION PROCEEDINGS | 2015年 / 47卷 / 04期

关键词：

SYSTEMIC TRANSTHYRETIN AMYLOIDOSIS; TRANSPLANTATION;

D O I：

10.1016/j.transproceed.2015.04.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 1995 Furtado et al performed the first domino transplantation using a donor liver with familial amyloid polyneuropathy (FAP), thereby increasing the pool of donors. Our experience showed that the onset of FAP symptoms occurs earlier in some patients. Patients with FAP acquired by transplantation are candidates for liver retransplantation to minimize the progression of symptoms. Liver retransplantation is considered to be a high-risk procedure and has lower survival compared with the first transplantation. We evaluated the risk of liver retransplantation in patients with acquired FAP. We did a retrospective analysis of these patients based on the records of perioperative data. From 1995 to 2004 we carried out 81 domino transplantations, of which 10 were submitted to liver retransplantation because of acquired FAP. The better outcomes in this group lead us to think that the liver retransplantation in patients with acquired FAP is not associated with the same risks of liver retransplantation in candidates with graft failure.

引用

页码：1012 / 1015

页数：4

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