Melohenryines A and B, two new indole alkaloids from Melodinus henryi

被引：9

作者：

Guo, Ling-Li ^{[1
]}

Yuan, Yu-Xi ^{[2
]}

He, Hong-Ping ^{[2
]}

Li, Shun-Lin ^{[1
]}

Zhang, Yu ^{[1
]}

Hao, Xiao-Jiang ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China

[2] Yunnan Univ TCM, Kunming 650500, Yunnan, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2017年 / 21卷

基金：

中国国家自然科学基金;

关键词：

Monoterpenoid indole alkaloids; Melohenryines A and B; Melodinus henryi; BISINDOLE ALKALOIDS; TENUICAUDATUS; HEMSLEYANUS;

D O I：

10.1016/j.phytol.2017.07.001

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new monoterpenoid indole alkaloids, melohenryines A and B (1 and 2), along with six known indole alkaloids, were isolated from the twigs and leaves of Melodinus henryi. Structures of the new alkaloids were established by extensive spectroscopic techniques including NMR spectroscopy and mass spectrometry. Melohenryine A (1) represents the first example of monoterpenoid indole alkaloids characterized an ester carbonyl group at C-19 position. All of the new compounds were evaluated for in vitro cytotoxicity against several human cancer cell lines.

引用

页码：179 / 182

页数：4

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