Effects of ethanolic extract of Iris germanica on lipid profile of rats fed on a high-fat diet

被引：49

作者：

Choudhary, MI ^{[1
]}

Naheed, S

Jalil, S

Alam, JM

Atta-ur-Rahman

机构：

[1] Univ Karachi, Int Ctr Chem Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan

[2] Liaquat Natl Post Grad Med Ctr, Dept Biochem & Chem Pathol, Karachi 74800, Pakistan

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2005年 / 98卷 / 1-2期

关键词：

Iris germanica; Iridaceae; hyperlipidemia; hypercholesterolemia; lipid-lowering activity;

D O I：

10.1016/j.jep.2005.01.013

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Ethanolic extract of Iris germanica rhizomes was investigated for hypolipidemic activity. L germanica belong to the family Iridaceae and has been used to treat liver and spleen ailments in traditional system of medicine. Two groups of Wistar rats were fed with high-fat diet and ethanolic extract of L germanica were administered orally in one group of rats, while other received saline for 10 weeks. Complete lipid profiles of experimental animals were determined by assessing serum levels of total lipids, triglycerides, cholesterol, high-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol. Results indicate that ethanolic extract of L germanica significantly lowered the lipid components especially, the cholesterol and triglycerides. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：217 / 220

页数：4

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