This study aims to determine the effects and the response to irrigation regimes (i) rainfed, (ii) deficit irrigation (DI), and (iii) full irrigation (FI) on wine and grape skin, seed and aromatic composition of grapevine cv. Bobal. The results show that the deficit irrigation treatment can modulate some important parameters of grapes and wine colour, and the aromatic composition of the grapes, with respect to rainfed and/or unlimited irrigation. In general, alcohol concentration and total acidity of the wines decreased with the application of water, while berry weight increased. Wine colour, total phenolics, and anthocyanins increased when water application was restricted due to the effect of water stress on anthocyanins, tannins and colour parameters of the grape skins and seeds. The water regime did not affect the seed polymeric concentration values, while the polymerization of grape skin tannins (higher mDP, aMW and %G) from the irrigated treatments, positively affected must astringency. Some aromatic precursors such as benzaldehyde, guaiacol, 4-ethylphenol, 4-vinylphenol, alpha-ionone, gamma-decalactone, syringaldehyde, and vainillin increased in the irrigated treatments with respect to rainfed. Benzanoic acid, 3-hydroxybenzaldehyde and octanoic acid content also increased with respect to the full irrigation treatment. These increases can favour metabolic pathways that enhance specific volatile aromas in the wines, affecting their sensory quality. The overall the results presented demonstrate the important role played by the irrigation regime in modulating Bobal grapes and wine composition.