Dynamic multivalent lactosides displayed on cyclodextrin beads dangling from polymer strings

被引：47
作者：
Nelson, A
Stoddart, JF
机构：
[1] Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
来源：
ORGANIC LETTERS | 2003年 / 5卷 / 21期
关键词：
D O I：
10.1021/ol0353464
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two-dimensional NMR spectroscopies.
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页码：3783 / 3786
页数：4
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