Carbazole-azine based fluorescence "off-on' sensor for selective detection of Cu2+ and its live cell imaging

被引:14
作者
Leslee, Denzil Britto Christopher [1 ]
Karuppannan, Sekar [1 ]
Vengaian, Karmegam Muthu [1 ]
Gandhi, Sivaraman [2 ]
Subramanian, Singaravadivel [3 ]
机构
[1] Anna Univ, Dept Chem, Univ Coll Engn, Dindigul 624622, India
[2] Inst Stem Cell Biol & Regenerat Med, Bangalore, Karnataka, India
[3] SSM Inst Engn & Technol, Dept Chem, Dindigul, India
关键词
azine; carbazole; cell imaging; copper ion; fluorescence; INDUCED EMISSION ENHANCEMENT; AQUEOUS-MEDIA; NEURODEGENERATIVE DISEASES; LIVING CELLS; COPPER IONS; METAL-IONS; PROBE; CHEMOSENSOR; HG2+; RECOGNITION;
D O I
10.1002/bio.3332
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A new carbazole-azine based fluorescent sensor was synthesized and characterized. The selectivity of the sensor for Cu2+ over other counter ions in a dimethyl sulfoxide/H2O mixture was shown through enhancement in fluorescence - an off to on transformation. The specificity of the probe towards Cu2+ was evident in ultraviolet/visible, fluorescence, Fourier transform infrared and mass studies. Application of the probe in the cell imaging and cytotoxicity of living cells is illustrated.
引用
收藏
页码:1354 / 1360
页数:7
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