Carbazole-azine based fluorescence "off-on' sensor for selective detection of Cu2+ and its live cell imaging

被引：14
作者：
Leslee, Denzil Britto Christopher [1 ]
Karuppannan, Sekar [1 ]
Vengaian, Karmegam Muthu [1 ]
Gandhi, Sivaraman [2 ]
Subramanian, Singaravadivel [3 ]
机构：
[1] Anna Univ, Dept Chem, Univ Coll Engn, Dindigul 624622, India
[2] Inst Stem Cell Biol & Regenerat Med, Bangalore, Karnataka, India
[3] SSM Inst Engn & Technol, Dept Chem, Dindigul, India
来源：
LUMINESCENCE | 2017年 / 32卷 / 07期
关键词：
azine; carbazole; cell imaging; copper ion; fluorescence; INDUCED EMISSION ENHANCEMENT; AQUEOUS-MEDIA; NEURODEGENERATIVE DISEASES; LIVING CELLS; COPPER IONS; METAL-IONS; PROBE; CHEMOSENSOR; HG2+; RECOGNITION;
D O I：
10.1002/bio.3332
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A new carbazole-azine based fluorescent sensor was synthesized and characterized. The selectivity of the sensor for Cu2+ over other counter ions in a dimethyl sulfoxide/H2O mixture was shown through enhancement in fluorescence - an off to on transformation. The specificity of the probe towards Cu2+ was evident in ultraviolet/visible, fluorescence, Fourier transform infrared and mass studies. Application of the probe in the cell imaging and cytotoxicity of living cells is illustrated.
引用
收藏
页码：1354 / 1360
页数：7
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共 88 条
  • [1] Aptamer-based label-free detection of PDGF using ruthenium(II) complex as luminescent probe
    Babu, E.
    Singaravadivel, S.
    Manojkumar, P.
    Krishnasamy, S.
    Kumar, G. Gnana
    Rajagopal, S.
    [J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2013, 405 (21) : 6891 - 6895
  • [2] A selective, long-lived deep-red emissive ruthenium(II) polypyridine complexes for the detection of BSA
    Babu, Eththilu
    Mareeswaran, Paulpandian Muthu
    Singaravadivel, Subramanian
    Bhuvaneswari, Jayaraman
    Rajagopal, Seenivasan
    [J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2014, 130 : 553 - 560
  • [3] Decreased risk of suicides and attempts during long-term lithium treatment: a meta-analytic review
    Baldessarini, Ross J.
    Tondo, Leonardo
    Davis, Paula
    Pompili, Maurizio
    Goodwin, Frederick K.
    Hennen, John
    [J]. BIPOLAR DISORDERS, 2006, 8 (05) : 625 - 639
  • [4] Design and synthesis of a new selective fluorescent chemical sensor for Cu2+ based on a Pyrrole moiety and a Fluorescein conjugate
    Bao, Xiaofeng
    Cao, Qiansheng
    Wu, Xiaolei
    Shu, Hai
    Zhou, Baojing
    Geng, Yougliang
    Zhu, Jing
    [J]. TETRAHEDRON LETTERS, 2016, 57 (08) : 942 - 948
  • [5] Neurodegenerative diseases and oxidative stress
    Barnham, KJ
    Masters, CL
    Bush, AI
    [J]. NATURE REVIEWS DRUG DISCOVERY, 2004, 3 (03) : 205 - 214
  • [6] Highly sensitive and selective "naked eye" sensing of Cu(II) by a novel amido-imine based receptor: a spectrophotometric and DFT study with practical application
    Bhattacharyya, Arghyadeep
    Ghosh, Soumen
    Guchhait, Nikhil
    [J]. RSC ADVANCES, 2016, 6 (34) : 28194 - 28199
  • [7] Unraveling the mechanisms involved in motor neuron degeneration in ALS
    Bruijn, LI
    Miller, TM
    Cleveland, DW
    [J]. ANNUAL REVIEW OF NEUROSCIENCE, 2004, 27 : 723 - 749
  • [8] THE WILSON DISEASE GENE IS A PUTATIVE COPPER TRANSPORTING P-TYPE ATPASE SIMILAR TO THE MENKES GENE
    BULL, PC
    THOMAS, GR
    ROMMENS, JM
    FORBES, JR
    COX, DW
    [J]. NATURE GENETICS, 1993, 5 (04) : 327 - 337
  • [9] Development in synthesis and electrochemical properties of thienyl derivatives of carbazole
    Cabaj, J
    Idzik, K
    Soloducho, J
    Chyla, A
    [J]. TETRAHEDRON, 2006, 62 (04) : 758 - 764
  • [10] Highly selective chromogenic and redox or fluorescent sensors of Hg2+ in aqueous environment based on 1,4-disubstituted azines
    Caballero, A
    Martínez, R
    Lloveras, V
    Ratera, I
    Vidal-Gancedo, J
    Wurst, K
    Tárraga, A
    Molina, P
    Veciana, J
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (45) : 15666 - 15667
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