Bone morphogenetic protein

被引：204

作者：

Xiao, Yong-Tao ^{[1
]}

Xiang, Li-Xin ^{[1
]}

Shao, Jian-Zhong ^{[1
]}

机构：

[1] Zhejiang Univ, Coll Life Sci, Hangzhou 310058, Peoples R China

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2007年 / 362卷 / 03期

关键词：

bone morphogenetic proteins; function; molecular signaling; medical application;

D O I：

10.1016/j.bbrc.2007.08.045

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor-beta superfamily. It has been demonstrated that BMPs had been involved in the regulation of cell proliferation, survival, differentiation and apoptosis. However, their hallmark ability is that play a pivotal role in inducing bone, cartilage, ligament, and tendon formation at both heterotopic and orthotopic sites. In this review, we mainly concentrate on BMP structure, function, molecular signaling and potential medical application. (c) 2007 Published by Elsevier Inc.

引用

页码：550 / 553

页数：4

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