A simple and sensitive fluorescent probe for specific detection of cysteine

被引:12
作者
Kang, Yan-Fei [1 ]
Qiao, Hai-Xia [1 ]
Meng, Ya-Li [1 ]
Xin, Zhen-Hui [1 ]
Ge, Li-Ping [1 ]
Zheng, Jin-Nan [1 ]
Wang, Yi-Na [1 ]
机构
[1] Hebei North Univ, Coll Lab Med, 11 Diamond St South, Zhangjiakou 075000, Hebei, Peoples R China
关键词
Fluorescence probe; cysteine; selectivity; bioimaging; SELECTIVE DETECTION; LIVING CELLS; COLORIMETRIC CHEMOSENSORS; RECENT PROGRESS; HOMOCYSTEINE; COUMARIN; GLUTATHIONE; MITOCHONDRIA; SUPEROXIDE; DESIGN;
D O I
10.1007/s12039-017-1326-y
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A fluorescent probe, with simplicity of structure and convenience of synthesis, is capable of detecting cysteine over other biothiols, such as homocysteine and glutathione. The detection limit of 60 nM and 190-fold increase in fluorescence intensity offer advantage for detection of Cys in biological systems. Furthermore, the probe 1 could be applied in bioimaging.
引用
收藏
页码:1219 / 1223
页数:5
相关论文
共 29 条
[1]  
[Anonymous], 1980, ANAL CHEM, V52, P2242
[2]   The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans [J].
Ball, Ronald O. ;
Courtney-Martin, Glenda ;
Pencharz, Paul B. .
JOURNAL OF NUTRITION, 2006, 136 (06) :1682S-1693S
[3]   Coumarin- and Rhodamine-Fused Deep Red Fluorescent Dyes: Synthesis, Photophysical Properties, and Bioimaging in Vitro [J].
Chen, Jianhong ;
Liu, Weimin ;
Zhou, Bingjiang ;
Niu, Guangle ;
Zhang, Hongyan ;
Wu, Jiasheng ;
Wang, Ying ;
Ju, Weigang ;
Wang, Pengfei .
JOURNAL OF ORGANIC CHEMISTRY, 2013, 78 (12) :6121-6130
[4]   Fluorescent and colorimetric probes for detection of thiols [J].
Chen, Xiaoqiang ;
Zhou, Ying ;
Peng, Xiaojun ;
Yoon, Juyoung .
CHEMICAL SOCIETY REVIEWS, 2010, 39 (06) :2120-2135
[5]   A simple and effective coumarin-based fluorescent probe for cysteine [J].
Dai, Xi ;
Wu, Qing-Hua ;
Wang, Peng-Chong ;
Tian, Jie ;
Xu, Yu ;
Wang, Sheng-Qing ;
Miao, Jun-Ying ;
Zhao, Bao-Xiang .
BIOSENSORS & BIOELECTRONICS, 2014, 59 :35-39
[6]   Mitochondria-Targeted Near-Infrared Fluorescent Off-On Probe for Selective Detection of Cysteine in Living Cells and in Vivo [J].
Han, Chunmiao ;
Yang, Huiran ;
Chen, Min ;
Su, Qianqian ;
Feng, Wei ;
Li, Fuyou .
ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (50) :27968-27975
[7]   Selective detection of cysteine over homocysteine and glutathione by a bis(bromoacetyl)fluorescein probe [J].
Hong, Keum-Hee ;
Lim, Soo-Yeon ;
Yun, Mi-Yeon ;
Lim, Joo-Won ;
Woo, Je-Hyuk ;
Kwon, Hyockman ;
Kim, Hae-Jo .
TETRAHEDRON LETTERS, 2013, 54 (23) :3003-3006
[8]   A NEW APPROACH FOR MEASUREMENT OF CYTOTOXICITY USING COLORIMETRIC ASSAY [J].
HUSSAIN, RF ;
NOURI, AME ;
OLIVER, RTD .
JOURNAL OF IMMUNOLOGICAL METHODS, 1993, 160 (01) :89-96
[9]   Recent progress in luminescent and colorimetric chemosensors for detection of thiols [J].
Jung, Hyo Sung ;
Chen, Xiaoqiang ;
Kim, Jong Seung ;
Yoon, Juyoung .
CHEMICAL SOCIETY REVIEWS, 2013, 42 (14) :6019-6031
[10]   Rapid and selective detection of cysteine over homocysteine and glutathione by a simple and effective coumarin-based fluorescent probe [J].
Kang, Yan-Fei ;
Qiao, Hai-Xia ;
Meng, Ya-Li ;
Cui, Sai-Jin ;
Han, Ya-Jun ;
Wu, Zhi-Yong ;
Wu, Jie ;
Jia, Xiao-Hui ;
Zhang, Xiao-Lei ;
Dai, Ming-Yan .
RSC ADVANCES, 2016, 6 (97) :94866-94869