Seroprevalence and Associated Risk Factors for Toxoplasma gondii Infection in Healthy Blood Donors: A Cross-Sectional Study in Sonora, Mexico

被引:23
作者
Alvarado-Esquivel, Cosme [1 ]
Rascon-Careaga, Antonio [2 ]
Hernandez-Tinoco, Jesus [3 ]
Guadalupe Corella-Madueno, Maria Alba [2 ]
Francisco Sanchez-Anguiano, Luis [3 ]
Lourdes Aldana-Madrid, Maria [4 ]
Velasquez-Vega, Edgar [5 ]
Quizan-Plata, Trinidad [2 ]
Luis Navarro-Henze, Jose [6 ]
Alberto Badell-Luzardo, Joel [7 ]
Maria Gastelum-Cano, Jose [2 ]
Liesenfeld, Oliver [8 ]
机构
[1] Juarez Univ Durango State, Fac Med & Nutr, Biomed Res Lab, Ave Univ S-N, Durango 34000, Dgo, Mexico
[2] Univ Sonora, Dept Chem & Biol Sci, Hermosillo 83000, Son, Mexico
[3] Juarez Univ Durango State, Inst Sci Res Dr Roberto Rivera Damm, Ave Univ S-N, Durango 34000, Dgo, Mexico
[4] Univ Sonora, Dept Res & Postgrad Food, Hermosillo 83000, Son, Mexico
[5] Secretary Hlth, State Ctr Blood Transfus, Hermosillo 83000, Son, Mexico
[6] Mexican Inst Social Insurance IMSS, Hermosillo 83190, Son, Mexico
[7] Secretaria Salud, Hermosillo 83270, Son, Mexico
[8] Charite, Campus Benjamin Franklin, Inst Microbiol & Hyg, Hindenburgdamm 27, D-12203 Berlin, Germany
关键词
ANTIBODIES; SEROEPIDEMIOLOGY; DISSEMINATION; DURANGO;
D O I
10.1155/2016/9597276
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Toxoplasma gondii (T. gondii) can be transmitted by blood transfusion. We determined the prevalence of T. gondii infection in healthy blood donors in Hermosillo city, Mexico, and the association of infection with T. gondii with the sociodemographic, clinical, and behavioral characteristics of blood donors. Four hundred and eight blood donors who attended two public blood banks in Hermosillo city were examined for anti-T. gondii IgG and IgM antibodies by using enzyme-linked immunoassays. Of the 408 blood donors (mean age 31.77 +/- 9.52; range 18-60 years old) studied, 55 (13.5%) were positive for anti-T. gondii IgG antibodies, and 12 (21.8%) of them were also positive for anti-T. gondii IgM antibodies. Multivariate analysis showed that seropositivity to T. gondii was associated with age (OR = 1.74; 95% CI: 1.03-2.94; P = 0.03) and tobacco use (OR = 2.09; 95% CI: 1.02-4.29; P = 0.04). Seropositivity to T. gondii was correlated with the number of pregnancies, deliveries, and cesarean sections. The seroprevalence of T. gondii infection in blood donors in Sonora is the highest reported in blood donors in northern Mexico so far. This is the first report of an association of T. gondii exposure and tobacco use. Further research to confirm this association is needed.
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页数:8
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