Surgical management of recurrent sinonasal mucosal melanoma: endoscopic or transfacial resection

被引:24
作者
Ledderose, G. J. [1 ]
Leunig, A. [1 ,2 ]
机构
[1] Univ Munich, Dept Otorhinolaryngol Head & Neck Surg, D-81377 Munich, Germany
[2] Dr Gaertner GmbH, ENT Clin Munich Bogenhausen, Rhinol Ctr, Munich, Germany
关键词
Sinonasal mucosal melanoma; SNMM; Local recurrence; Survival; Relapse-free time; Endonasal; Extranasal; MALIGNANT-MELANOMA; PARANASAL SINUSES; POSTOPERATIVE RADIOTHERAPY; EXPERIENCE; NECK; HEAD; TRACT; NOSE; OUTCOMES; SURGERY;
D O I
10.1007/s00405-014-3119-y
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Sinonasal mucosal melanoma (SNMM) is associated with poor prognosis. Local recurrence is common and represents a major problem in the therapy. Wide resection surgery is usually applied. However, given the almost futile prognosis, optimal symptom control may be preferable to wide resection at all costs. The aim of our study was to analyze the outcome in patients with recurrent SNMM treated by transfacial radical surgery or by a less invasive endoscopically controlled approach. Patients with recurrent grade III or IV staged SNMM who presented to our ENT department between 2000 and 2010 were either treated by transfacial (n = 10) or endoscopically controlled surgery (n = 12). The patients' charts were reviewed for clinical symptoms, relapse-free time and survival time. Clinical symptoms improved after surgery. The morbidity after endoscopic surgery was significantly lower than after transfacial surgery. The chosen surgical technique did neither affect relapse-free nor survival time. When treating recurrent SNMM, the comparatively gentle and less mutilating endoscopic approach proved to be a sufficient surgical procedure, being not inferior to aggressive surgery with respect to recurrence and survival rate.
引用
收藏
页码:351 / 356
页数:6
相关论文
共 26 条
[1]  
Bradley Patrick J, 2006, Curr Opin Otolaryngol Head Neck Surg, V14, P100
[2]   Experience with mucosal melanoma of the nose and paranasal sinuses [J].
Bridger, AG ;
Smee, D ;
Baldwin, MAR ;
Kwok, B ;
Bridger, GP .
ANZ JOURNAL OF SURGERY, 2005, 75 (04) :192-197
[3]  
Chang AE, 1998, CANCER, V83, P1664, DOI 10.1002/(SICI)1097-0142(19981015)83:8<1664::AID-CNCR23>3.0.CO
[4]  
2-G
[5]  
Chiu NT, 1996, ARCH OTOLARYNGOL, V122, P985
[6]  
Christopherson K., 2013, AM J CLIN ONCOL
[7]   Malignant melanoma of nasal cavity and paranasal sinuses: report of 24 patients and literature review [J].
Clifton, N. ;
Harrison, L. ;
Bradley, P. J. ;
Jones, N. S. .
JOURNAL OF LARYNGOLOGY AND OTOLOGY, 2011, 125 (05) :479-485
[8]   Sinonasal melanoma: A clinicopathologic review of 61 cases [J].
Dauer, Eileen H. ;
Lewis, Jean E. ;
Rohlinger, Audrey L. ;
Weaver, Amy L. ;
Olsen, Kerry D. .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2008, 138 (03) :347-352
[9]  
Dzepina D, 2012, COLLEGIUM ANTROPOL, V36, P179
[10]   Demographics and Treatment Trends in Sinonasal Mucosal Melanoma [J].
Gal, Thomas J. ;
Silver, Natalie ;
Huang, Bin .
LARYNGOSCOPE, 2011, 121 (09) :2026-2033