The stiffness of transplanted kidneys changes with time after renal transplantation

被引：2

作者：

Chen, Shaona ^{[1
]}

Li, Jin ^{[1
]}

Zeng, Bidan ^{[1
]}

Zhu, Zhimin ^{[1
]}

Luo, Yanhua ^{[1
]}

Chen, Fei ^{[1
]}

Qiu, Shaodong ^{[1
]}

机构：

[1] Guangzhou Med Univ, Dept Ultrasound, Affiliated Hosp 2, 250 Changgang East Rd, Guangzhou, Guangdong, Peoples R China

来源：

ACTA RADIOLOGICA | 2022年 / 63卷 / 08期

关键词：

Renal transplantation; shear wave elastography; stiffness; ultrasound; TISSUE ELASTICITY QUANTIFICATION; RADIATION FORCE IMPULSE; TRANSIENT ELASTOGRAPHY; REPERFUSION INJURY; ALLOGRAFT FIBROSIS;

D O I：

10.1177/02841851211030770

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Background Kidney transplantation is one of the most effective ways to treat end-stage kidney disease. However, 5000 renal transplant recipients start or restart dialysis because of chronic allograft nephropathy (CAN) every year in the United States. Detecting changes in the stiffness of transplanted kidneys can help diagnose transplanted kidney disease. Purpose To explore changes in the stiffness of transplanted kidneys after renal transplantation using shear wave elastography (SWE). Material and Methods This study conducted consecutive follow-up observations on 10 patients after kidney transplantation. SWE examination was performed in the first week, second week, first month, second month, third month, fourth month, fifth month, and sixth month after surgery. This study also analyzed the graft stiffness of 86 patients with stable renal function recovery one month after surgery. Results The results show that there is a change in the stiffness of the transplanted kidney over time after renal transplantation. It decreases rapidly within one month after renal transplantation and tends to be stable after one month. The mean renal cortical and pyramidal stiffness of patients with stable renal function were 28.48 +/- 4.27 kPa and 21.97 +/- 3.90 kPa, respectively. Conclusion Consecutive stiffness measurement of transplanted kidneys is an effective method for monitoring the function of transplanted kidneys. According to the change in transplanted kidney stiffness, we can designate a more scientific review plan to determine the functional status of the transplanted kidney.

引用

页码：1134 / 1141

页数：8

共 15 条

[11] ARFI-based tissue elasticity quantification and kidney graft dysfunction: First clinical experiences [J].

Stock, K. F. ;

Klein, B. S. ;

Cong, M. T. Vo ;

Regenbogen, C. ;

Kemmner, S. ;

Buettner, M. ;

Wagenpfeil, S. ;

Matevossian, E. ;

Renders, L. ;

Heemann, U. ;

Kuechle, C. .

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 2011, 49 (1-4) :527-535

[12] ARFI-based tissue elasticity quantification in comparison to histology for the diagnosis of renal transplant fibrosis [J].

Stock, K. F. ;

Klein, B. S. ;

Cong, M. T. Vo ;

Sarkar, O. ;

Roemisch, M. ;

Regenbogen, C. ;

Buettner, M. ;

Schuster, T. ;

Matevossian, E. ;

Amann, K. ;

Clevert, D. A. ;

Heemann, U. ;

Kuechle, C. .

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 2010, 46 (2-3) :139-148

[13] Acoustic Radiation Force Impulse Imaging of the Transplant Kidney: Correlation Between Cortical Stiffness and Arterial Resistance in Early Post-transplant Period [J].

Wang, H. -K. ;

Lai, Y. -C. ;

Lin, Y. -H. ;

Chiou, H. J. ;

Chou, Y. -H. .

TRANSPLANTATION PROCEEDINGS, 2017, 49 (05) :1001-1004

[14] PREDICTION OF RENAL ALLOGRAFT ACUTE REJECTION USING A NOVEL NON-INVASIVE MODEL BASED ON ACOUSTIC RADIATION FORCE IMPULSE [J].

Yang, Cheng ;

Jin, Yunjie ;

Wu, Shengdi ;

Li, Long ;

Hu, Mushuang ;

Xu, Ming ;

Rong, Ruiming ;

Zhu, Tongyu ;

He, Wanyuan .

ULTRASOUND IN MEDICINE AND BIOLOGY, 2016, 42 (09) :2167-2179

[15] Ischemia-Reperfusion Injury Reduces Long Term Renal Graft Survival: Mechanism and Beyond [J].

Zhao, Hailin ;

Alam, Azeem ;

Soo, Aurelie Pac ;

George, Andrew J. T. ;

Ma, Daqing .

EBIOMEDICINE, 2018, 28 :31-42

← 1 2 →