Kidney damage in COVID-19

被引:3
|
作者
Burtey, Stephane [1 ,2 ]
Sallee, Marion [1 ,2 ]
机构
[1] Aix Marseille Univ, INSERM, INRAE, C2VN, F-13005 Marseille, France
[2] Aix Marseille Univ, Ctr Nephrol & Transplantat Renale, Hop Concept, 147 Blvd Baille, F-13005 Marseille, France
来源
NEPHROLOGIE & THERAPEUTIQUE | 2021年 / 17卷 / 04期
关键词
Acute tubular necrosis; COVID-19; Focal segmental glomerulosclerosis; Proximal tubulopathy; SARS-CoV-2; CORONAVIRUS; TRANSMISSION; INJURY;
D O I
10.1016/j.nephro.2021.06.002
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
COVID-19 is a disease caused by the RNA virus SARS-CoV-2. It is characterised by an attack mainly affecting the respiratory system. There is renal involvement which is characterised by three main types of damage, acute tubular necrosis occurring in the most severe cases, proximal tubulopathy which is a prognostic marker of the disease and segmental and focal hyalinosis occurring in a genetically predisposed terrain. The pathophysiology of SARS-CoV-2 renal involvement is not yet defined. The direct role of the virus is debated, whereas the cytokine storm and the hypoxic and thrombotic complications seem more important. The long-term outcome of the renal damage appears to be quite good. Long-term follow-up will allow us to say whether the renal damage is part of the long COVID. (C) 2021 Societe francophone de nephrologie, dialyse et transplantation. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:203 / 207
页数:5
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