Performance Study of a Torsional Wave Sensor and Cervical Tissue Characterization

被引:24
作者
Callejas, Antonio [1 ]
Gomez, Antonio [2 ]
Melchor, Juan [1 ,3 ]
Riveiro, Miguel [1 ]
Masso, Paloma [1 ,3 ]
Torres, Jorge [1 ]
Lopez-Lopez, Modesto T. [4 ]
Rus, Guillermo [1 ,3 ]
机构
[1] Univ Granada, Dept Struct Mech, E-18071 Granada, Spain
[2] UCL, Dept Mech Engn, London WC1E 7JE, England
[3] Biosanitary Res Inst, Granada 18012, Spain
[4] Univ Granada, Dept Appl Phys, E-18071 Granada, Spain
关键词
torsional wave sensor; tissue mimicking phantom; cervical tissue; rheological model; rheometry experiment; sensitivity study; complex shear modulus; VISCOELASTIC PROPERTIES; RADIATION FORCE; ELASTOGRAPHY; ULTRASOUND; ELASTICITY; DISPERSION; VISCOSITY; RHEOMETRY; MODULUS; MUCOSA;
D O I
10.3390/s17092078
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A novel torsional wave sensor designed to characterize mechanical properties of soft tissues is presented in this work. Elastography is a widely used technique since the 1990s to map tissue stiffness. Moreover, quantitative elastography uses the velocity of shear waves to achieve the shear stiffness. This technique exhibits significant limitations caused by the difficulty of the separation between longitudinal and shear waves and the pressure applied while measuring. To overcome these drawbacks, the proposed torsional wave sensor can isolate a pure shear wave, avoiding the possibility of multiple wave interference. It comprises a rotational actuator disk and a piezoceramic receiver ring circumferentially aligned. Both allow the transmission of shear waves that interact with the tissue before being received. Experimental tests are performed using tissue mimicking phantoms and cervical tissues. One contribution is a sensor sensitivity study that has been conducted to evaluate the robustness of the new proposed torsional wave elastography (TWE) technique. The variables object of the study are both the applied pressure and the angle of incidence sensor-phantom. The other contribution consists of a cervical tissue characterization. To this end, three rheological models have fit the experimental data and a static independent testing method has been performed. The proposed methodology permits the reconstruction of the mechanical constants from the propagated shear wave, providing a proof of principle and warranting further studies to confirm the validity of the results.
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页数:19
相关论文
共 46 条
[41]   The impact of aging and gender on brain viscoelasticity [J].
Sack, Ingolf ;
Beierbach, Bernd ;
Wuerfel, Jens ;
Klatt, Dieter ;
Hamhaber, Uwe ;
Papazoglou, Sebastian ;
Martus, Peter ;
Braun, Juergen .
NEUROIMAGE, 2009, 46 (03) :652-657
[42]  
Taylor RobertL., 1987, FEAP-ein finite element analysis programm
[43]   Generalized response of a sphere embedded in a viscoelastic medium excited by an ultrasonic radiation force [J].
Urban, Matthew W. ;
Nenadic, Ivan Z. ;
Mitchell, Scott A. ;
Chen, Shigao ;
Greenleaf, James F. .
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 2011, 130 (03) :1133-1141
[44]   Quantitative viscoelastic parameters measured by harmonic motion imaging [J].
Vappou, Jonathan ;
Maleke, Caroline ;
Konofagou, Elisa E. .
PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (11) :3579-3594
[45]  
Walden A., 1994, U.S. Patent, Patent No. [5,321,333 A, 5321333]
[46]   Congruence of imaging estimators and mechanical measurements of viscoelastic properties of soft tissues [J].
Zhang, Man ;
Castaneda, Benjamin ;
Wu, Zhe ;
Nigwekar, Priya ;
Joseph, Jean V. ;
Rubens, Deborah J. ;
Parker, Kevin J. .
ULTRASOUND IN MEDICINE AND BIOLOGY, 2007, 33 (10) :1617-1631