Surface-anchored liquid crystal droplets for the semi-quantitative detection of Aflatoxin B1 in food samples

被引：17

作者：

Cheng, Supan ^{[1
,3
]}

Khan, Mashooq ^{[1
,3
]}

Yin, Fangchao ^{[1
,3
]}

Ma, Chunxia ^{[1
,3
]}

Yuan, Jinpeng ^{[1
,3
]}

Jiang, Ting ^{[1
,3
]}

Liu, Xuefeng ^{[2
]}

Hu, Qiongzheng ^{[1
,3
]}

机构：

[1] Qilu Univ Technol, Shandong Acad Sci, Sch Pharmaceut Sci, Jinan 250014, Peoples R China

[2] Jiangnan Univ, Key Lab Synthet & Biol Colloids, Minist Educ, Wuxi 214122, Peoples R China

[3] Qilu Univ Technol, Shandong Acad Sci, Shandong Anal & Test Ctr, Jinan 250014, Peoples R China

来源：

FOOD CHEMISTRY | 2022年 / 390卷

关键词：

Aflatoxin B1; Mycotoxin; Liquid crystal; Sessile droplet; Aptamer; MYCOTOXINS;

D O I：

10.1016/j.foodchem.2022.133202

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Aflatoxin B1 (AFB1) is a common food mycotoxin that can cause various diseases. Therefore, reliable detection methods are required to ensure food safety against mycotoxins. In this study, we design a liquid-crystal (LC) based assay for rapid detection of AFB1 in food samples. The surface-anchored LC droplets on glass (5CB(SADrop)) are obtained via a solvent evaporation method. The 5CB(SADrop) displays a four-leaf clover appearance that corresponds to an escape-radial configuration in a mixture of CTAB and AFB1 aptamer. Interestingly, they adopt a radial configuration in the mixture of CTAB, AFB1, and its aptamer. Using this approach, AFB1 can be detected using only 1 mu L of the aqueous solution with a minimum detection concentration of 10 pg/mL. This LC-based sensing platform provides simple operation, remarkable sensitivity, high selectivity, low cost, and excellent portability without the use of any bulky instrument, which is very promising in rapid on-field detection of mycotoxins.

引用

页数：8

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