Functionalized benzylic magnesium reagents through a sulfur-magnesium exchange

被引：64

作者：

Stoll, AH ^{[1
]}

Krasovskiy, A ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 04期

关键词：

benzylic organometallic compounds; cross-coupling; fragmentation; Grignard reaction; organocopper compounds;

D O I：

10.1002/anie.200501882

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Switch it: lodobiphenyl thioethers readily undergo an iodine-magnesium exchange followed by, after the addition of tBuOLi, an intramolecular sulfur-magnesium exchange, which provides benzylic magnesium reagents in excellent yield through a fragmentation reaction. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：606 / 609

页数：4

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