Electrosprayed gelatin submicroparticles as edible carriers for the encapsulation of polyphenols of interest in functional foods

被引:132
作者
Gomez-Mascaraque, Laura G. [1 ]
Maria Lagaron, Jose [1 ]
Lopez-Rubio, Amparo [1 ]
机构
[1] CSIC, IATA, Novel Mat & Nanotechnol Grp, Valencia 46980, Spain
关键词
Electrospray; Encapsulation; Gelatin; Antioxidant; Epigallocatechin gallate; Functional food; EPIGALLOCATECHIN-3-GALLATE EGCG; ANTIOXIDANT ACTIVITY; FIBER FORMATION; RELEASE; ACID; DELIVERY; FILMS; NANOPARTICLES; CATECHINS; NANOFIBER;
D O I
10.1016/j.foodhyd.2015.03.006
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
In this work, the potential of the electrospraying technique to obtain food-grade gelatin capsules in the submicron range for sensitive bioactive protection was explored, studying the influence of the protein concentration on the size and morphology of the obtained particles. Gelatin was selected as encapsulating material because, being commonly used as a food ingredient, it possesses unique gelation properties and is commercially available at a low cost. The electrosprayed matrices were used to encapsulate a model antioxidant molecule, (-)-epigallocatechin gallate (EGCG). Very high encapsulation efficiencies, close to 100%, were achieved, and the antioxidant activity of the bioactive was fully retained upon encapsulation. The EGCG release profiles showed a delayed release of the encapsulated antioxidant in aqueous solutions. Furthermore, while free EGCG in PBS lost a 30% of their antioxidant activity being completely degraded in 100 h, encapsulated EGCG retained its whole antioxidant activity within this time period. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:42 / 52
页数:11
相关论文
共 61 条
[1]   Antioxidative activity and emulsifying properties of cuttlefish skin gelatin-tannic acid complex as influenced by types of interaction [J].
Aewsiri, Tanong ;
Benjakul, Soottawat ;
Visessanguan, Wonnop ;
Wierenga, Peter A. ;
Gruppen, Harry .
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES, 2010, 11 (04) :712-720
[2]   Characterization and thermal behavior of PrMO3 (M = Co or Ni) ceramic materials obtained from gelatin [J].
Aquino, F. M. ;
Melo, D. M. A. ;
Pimentel, P. M. ;
Braga, R. M. ;
Melo, M. A. F. ;
Martinelli, A. E. ;
Costa, A. F. .
MATERIALS RESEARCH BULLETIN, 2012, 47 (09) :2605-2609
[3]   ALTERNATIVE FATTY FOOD SIMULANTS FOR MIGRATION TESTING OF POLYMERIC FOOD CONTACT MATERIALS [J].
BANER, A ;
BIEBER, W ;
FIGGE, K ;
FRANZ, R ;
PIRINGER, O .
FOOD ADDITIVES AND CONTAMINANTS, 1992, 9 (02) :137-148
[4]   Formulation and characterization of polyphenol-loaded lipid nanocapsules [J].
Barras, A. ;
Mezzetti, A. ;
Richard, A. ;
Lazzaroni, S. ;
Roux, S. ;
Melnyk, P. ;
Betbeder, D. ;
Monfilliette-Dupont, N. .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2009, 379 (02) :270-277
[5]   Electrospinning: A fascinating fiber fabrication technique [J].
Bhardwaj, Nandana ;
Kundu, Subhas C. .
BIOTECHNOLOGY ADVANCES, 2010, 28 (03) :325-347
[6]   Electrospraying of polymers with therapeutic molecules: State of the art [J].
Bock, N. ;
Dargaville, T. R. ;
Woodruff, M. A. .
PROGRESS IN POLYMER SCIENCE, 2012, 37 (11) :1510-1551
[7]   Electrohydrodynamics: A facile technique to fabricate drug delivery systems [J].
Chakraborty, Syandan ;
Liao, I-Chien ;
Adler, Andrew ;
Leong, Kam W. .
ADVANCED DRUG DELIVERY REVIEWS, 2009, 61 (12) :1043-1054
[8]  
Cooper I, 1998, FOOD ADDIT CONTAM, V15, P72
[9]   Thermal and hydrolytic degradation of electrospun fish gelatin membranes [J].
Correia, D. M. ;
Padrao, J. ;
Rodrigues, L. R. ;
Dourado, F. ;
Lanceros-Mendez, S. ;
Sencadas, V. .
POLYMER TESTING, 2013, 32 (05) :995-1000
[10]   INFRARED SPECTROSCOPY OF COLLAGEN AND COLLAGEN-LIKE POLYPEPTIDES [J].
DOYLE, BB ;
BENDIT, EG ;
BLOUT, ER .
BIOPOLYMERS, 1975, 14 (05) :937-957