Can quantitative pharmacology improve productivity in pharmaceutical research and development?

被引：4
|
作者：
Patel, Mayankbhai [1 ]
Bueters, Tjerk [1 ]
机构：
[1] Merck & Co Inc, Dept Pharmacokinet Pharmacodynam & Drug Metab PPD, Galloping Hill Rd, Kenilworth, NJ 2000 USA
来源：
EXPERT OPINION ON DRUG DISCOVERY | 2020年 / 15卷 / 10期
关键词：
Translational biomarkers; R&D productivity; model-informed drug discovery and development (MID3); quantitative pharmacology; modeling and simulation; IMPACT; BIOMARKERS; THERAPIES;
D O I：
10.1080/17460441.2020.1776257
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1111 / 1113
页数：3
相关论文
共 50 条
  • [31] Quantitative system pharmacology as a legitimate approach to examine extrapolation strategies used to support pediatric drug development
    Azer, Karim
    Barrett, Jeffrey S.
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2022, 11 (07): : 797 - 804
  • [32] Development Research: The Role of Supply Chain Management on Increasing the Company's Productivity
    Wahyuni, Hana Catur
    Sumarmi, Wiwik
    PROCEEDINGS OF THE 1ST INTERNATIONAL CONFERENCE ON INTELLECTUALS' GLOBAL RESPONSIBILITY (ICIGR 2017), 2017, 125 : 6 - 9
  • [33] The Impact of Translational Research in Breast Cancer Care: Can We Improve the Therapeutic Scenario?
    Buono, Giuseppe
    Schettini, Francesco
    Perri, Francesco
    Arpino, Grazia
    Bianco, Roberto
    Criscitiello, Carmen
    De Placido, Sabino
    Giuliano, Mario
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 18 (06) : 832 - 836
  • [34] Editorial: Model-informed decision making in the preclinical stages of pharmaceutical research and development
    Li, Rui
    Craig, Morgan
    D'Argenio, David Z.
    Betts, Alison
    Mager, Donald E.
    Maurer, Tristan S.
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [35] Inclusion of legume and integrated use of organic and inorganic nutrient sources can improve the productivity and qualitative traits of oats straw
    Yadav, M. R.
    Singh, Magan
    Kumar, Rakesh
    Ram, Hardev
    Meena, R. K.
    Makarana, Govind
    Kumar, Dinesh
    Dutta, Susanta
    JOURNAL OF PLANT NUTRITION, 2022, 45 (13) : 1991 - 2002
  • [36] Can New Private Shareholders Help Improve SOEs' Total Factor Productivity? Evidence from the Chinese Listed SOEs
    Xie, Huobao
    Yang, Weiwei
    Li, Qingyuan
    ANNALS OF ECONOMICS AND FINANCE, 2022, 23 (01): : 23 - 62
  • [37] How Insights from the "New" JDM Research Can Improve Auditor Judgment: Fundamental Research Questions and Methodological Advice
    Griffith, Emily E.
    Kadous, Kathryn
    Young, Donald
    AUDITING-A JOURNAL OF PRACTICE & THEORY, 2016, 35 (02): : 1 - 22
  • [38] Can entrepreneurial orientation improve sustainable development through leveraging internal lean practices?
    Chavez, Roberto
    Yu, Wantao
    Jajja, Muhammad Shakeel Sadiq
    Lecuna, Antonio
    Fynes, Brian
    BUSINESS STRATEGY AND THE ENVIRONMENT, 2020, 29 (06) : 2211 - 2225
  • [39] Can the outside-view approach improve planning decisions in software development projects?
    Shmueli, Ofira
    Pliskin, Nava
    Fink, Lior
    INFORMATION SYSTEMS JOURNAL, 2016, 26 (04) : 395 - 418
  • [40] Can public transportation development improve urban air quality? Evidence from China
    Bi, Shenghao
    Hu, Jin
    Shao, Liangshan
    Feng, Tianchu
    Appolloni, Andrea
    URBAN CLIMATE, 2024, 54
12345