Can quantitative pharmacology improve productivity in pharmaceutical research and development?

被引:4
|
作者
Patel, Mayankbhai [1 ]
Bueters, Tjerk [1 ]
机构
[1] Merck & Co Inc, Dept Pharmacokinet Pharmacodynam & Drug Metab PPD, Galloping Hill Rd, Kenilworth, NJ 2000 USA
关键词
Translational biomarkers; R&D productivity; model-informed drug discovery and development (MID3); quantitative pharmacology; modeling and simulation; IMPACT; BIOMARKERS; THERAPIES;
D O I
10.1080/17460441.2020.1776257
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:1111 / 1113
页数:3
相关论文
共 50 条
  • [1] Quantitative Systems Pharmacology can reduce attrition and improve productivity in pharmaceutical research and development
    Leil, Tarek A.
    Bertz, Richard
    FRONTIERS IN PHARMACOLOGY, 2014, 5
  • [2] The convergence of pharmacometrics and quantitative systems pharmacology in pharmaceutical research and development
    Joshi, Amita
    Ramanujan, Saroja
    Jin, Jin Y.
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 182
  • [3] The promises of quantitative systems pharmacology modelling for drug development
    Knight-Schrijver, V. R.
    Chelliah, V.
    Cucurull-Sanchez, L.
    Le Novere, N.
    COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2016, 14 : 363 - 370
  • [4] Globalization of quantitative pharmacology: First International Symposium of Quantitative Pharmacology in Drug Development and Regulation
    Barrett, Jeffrey S.
    Shi, Jun
    Xie, Hai-tang
    Huang, Xiao-hui
    Fossler, Michael J.
    Sun, Rui-yuan
    JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 48 (07) : 787 - 792
  • [5] Proteomics in pharmaceutical research and development
    Cutler, Paul
    Voshol, Hans
    PROTEOMICS CLINICAL APPLICATIONS, 2015, 9 (7-8) : 643 - 650
  • [6] The Role of Quantitative Pharmacology in an Academic Translational Research Environment
    Jeffrey S. Barrett
    The AAPS Journal, 2008, 10 : 9 - 14
  • [7] The role of quantitative pharmacology in an academic translational research environment
    Barrett, Jeffrey S.
    AAPS JOURNAL, 2008, 10 (01) : 9 - 14
  • [8] Application of Quantitative Pharmacology in Development of Therapeutic Monoclonal Antibodies
    Mohammad Tabrizi
    Cherryl Funelas
    Hamza Suria
    The AAPS Journal, 2010, 12 : 592 - 601
  • [9] Application of Quantitative Pharmacology in Development of Therapeutic Monoclonal Antibodies
    Tabrizi, Mohammad
    Funelas, Cherryl
    Suria, Hamza
    AAPS JOURNAL, 2010, 12 (04): : 592 - 601
  • [10] Can the digital transformation of pharmaceutical enterprises' finance improve healthcare equity?
    Fan, Cunbin
    Zou, Guohao
    Yang, Chufeng
    Zhao, Ziqiang
    FINANCE RESEARCH LETTERS, 2024, 67