Total synthesis of (+)-rugulosin and (+)-2,2′-epi-cytoskyrin A through cascade reactions

被引：47

作者：

Nicolaou, KC

Lim, YH

Papageorgiou, CD

Piper, JL

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

[3] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 48期

关键词：

anthraquinones; biomimetic synthesis; Michael reaction; natural products; total synthesis;

D O I：

10.1002/anie.200503678

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) The cytoskyrin cascade: The total syntheses of the bisanthraquinones 2 (+)-2,2′-epi-cytoskyrin A (R2 = OMe) and (+)-rugulosin (R2 = Me) has been achieved through a cascade sequence from anthradihydroquinone monomeric units 1. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：7917 / 7921

页数：5

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