The Danish Twin Registry

被引：87
作者：
Skytthe, Axel [1 ]
Kyvik, Kirsten Ohm [2 ]
Holm, Niels Vilstrup [3 ]
Christensen, Kaare [1 ,4 ,5 ]
机构：
[1] Univ So Denmark, Danish Twin Registry, Inst Publ Hlth, DK-5000 Odense C, Denmark
[2] Univ So Denmark, Inst Reg Hlth Serv Res, DK-5000 Odense C, Denmark
[3] Odense Univ Hosp, Dept Oncol, DK-5000 Odense, Denmark
[4] Odense Univ Hosp, Dept Clin Biochem & Pharmacol, DK-5000 Odense, Denmark
[5] Odense Univ Hosp, Dept Clin Genet, DK-5000 Odense, Denmark
来源：
SCANDINAVIAN JOURNAL OF PUBLIC HEALTH | 2011年 / 39卷
基金：
新加坡国家研究基金会;
关键词：
Twin register; ascertainment; multiple births; Denmark;
D O I：
10.1177/1403494810387966
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Introduction: The Danish Twin Registry is a unique source for studies of genetic, familial and environmental factors on life events, health conditions and diseases. Content: More than 85,000 twin pairs born 1870-2008 in Denmark. Validity and coverage: Four main ascertainment methods have been employed. Completeness of ascertainment varies according to birth cohorts. For birth cohorts 1870-1930 both twins should survive to age 6 years. From 1931-1968 72% of all twin pairs has been ascertained, with complete ascertainment of all live born twins since 1968. Conclusion: Because twins have been identified independent of traits and on a population basis, the Danish Twin Registry is well suited for studies to understand the influence of genetic and environmental factors for a wide variety of diseases and traits.
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收藏
页码：75 / 78
页数：4
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