Synthesis and Cytotoxic Activity of 1,3,5-Triazinane Derivatives Based on Primary Amines and Amino Acids Esters

被引：0
|
作者：
Kireeva, D. R. [1 ]
Sadretdinov, S. S. [1 ]
Musina, A., I [1 ]
Ishmetova, D., V [2 ]
Vakhitov, V. A. [2 ]
Murinov, Yu, I [1 ]
Dokichev, V. A. [1 ]
机构：
[1] Russian Acad Sci, Ufa Inst Chem, Ufa Fed Res Ctr, Ufa 450054, Russia
[2] Russian Acad Sci, Inst Biochem & Genet, Ufa Sci Ctr, Ufa 450054, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2022年 / 92卷 / 01期
关键词：
1; 3; 5-triazinane; cytotoxic activity; amino acid; cyclocondensation;
D O I：
10.1134/S1070363222010054
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A series of 1,3,5-triazinane derivatives was synthesized and their cytotoxic activity was studied in vitro on normal cell line (HEK293) and tumor cell lines (SH-SY5Y, MCF-7, A549). It was shown that the studied compounds have moderate cytotoxic activity against normal and tumor cell lines.
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收藏
页码：24 / 28
页数：5
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