Reproducibility of subregional trabecular bone micro-architectural measures derived from 7-Tesla magnetic resonance images

被引:17
作者
Chang, Gregory [1 ]
Wang, Ligong [1 ]
Liang, Guoyuan [2 ,3 ]
Babb, James S. [1 ]
Saha, Punam K. [2 ,3 ]
Regatte, Ravinder R. [1 ]
机构
[1] NYU, Langone Med Ctr, Ctr Biomed Imaging, Dept Radiol, New York, NY 10016 USA
[2] Univ Iowa, Dept Elect & Comp Engn, Iowa City, IA 52242 USA
[3] Univ Iowa, Dept Radiol, Seamans Ctr Engn Arts & Sci 3414, Iowa City, IA 52242 USA
基金
美国国家卫生研究院;
关键词
Ultra high field; 7; Tesla; MRI; Trabecular bone; Micro-architecture; Knee; ARTICULAR-CARTILAGE; MRI; INTERRELATIONSHIP; PARAMETERS;
D O I
10.1007/s10334-010-0243-6
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
High-resolution magnetic resonance imaging (MRI) of trabecular bone combined with quantitative image analysis represents a powerful technique to gain insight into trabecular bone micro-architectural derangements in osteoporosis and osteoarthritis. The increased signal-to-noise ratio of ultra high-field MR (a parts per thousand yen7 Tesla) permits images to be obtained with higher resolution and/or decreased scan time compared to scanning at 1.5/3T. In this small feasibility study, we show high measurement precision for subregional trabecular bone micro-architectural analysis performed on 7T knee MR images. The results provide further support for the use of trabecular bone measures as biomarkers in clinical studies of bone disorders.
引用
收藏
页码:121 / 125
页数:5
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