Stem cells in veterinary medicine

被引：103

作者：

Fortier, Lisa A. ^{[1
]}

Travis, Alexander J. ^{[2
]}

机构：

[1] Cornell Univ, Dept Clin Sci, Ithaca, NY 14850 USA

[2] Cornell Univ, James A Baker Inst Anim Hlth, Ithaca, NY 14850 USA

来源：

STEM CELL RESEARCH & THERAPY | 2011年 / 2卷

基金：

美国国家卫生研究院;

关键词：

MESENCHYMAL STROMAL CELLS; GENE-EXPRESSION PATTERNS; DIGITAL FLEXOR TENDON; PLATELET-RICH PLASMA; BONE-MARROW; ADIPOSE-TISSUE; TESTIS TISSUE; GERM-CELLS; SPERMATOGENESIS; TRANSPLANTATION;

D O I：

10.1186/scrt50

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

The stem cell field in veterinary medicine continues to evolve rapidly both experimentally and clinically. Stem cells are most commonly used in clinical veterinary medicine in therapeutic applications for the treatment of musculoskeletal injuries in horses and dogs. New technologies of assisted reproduction are being developed to apply the properties of spermatogonial stem cells to preserve endangered animal species. The same methods can be used to generate transgenic animals for production of pharmaceuticals or for use as biomedical models. Small and large animal species serve as valuable models for preclinical evaluation of stem cell applications in human beings and in veterinary patients in areas such as spinal cord injury and myocardial infarction. However, these applications have not been implemented in the clinical treatment of veterinary patients. Reviews on the use of animal models for stem cell research have been published recently. Therefore, in this review, animal model research will be reviewed only in the context of supporting the current clinical application of stem cells in veterinary medicine.

引用

页数：6