Efficacy of 5-Azacytidine in a TET2 mutated angioimmunoblastic T cell lymphoma

被引：45

作者：

Cheminant, Morgane ^{[1
]}

Bruneau, Julie ^{[2
,3
]}

Kosmider, Olivier ^{[4
]}

Lefrere, Francois ^{[5
]}

Delarue, Richard ^{[1
]}

Gaulard, Philippe ^{[6
]}

Radford, Isabelle ^{[7
]}

Derrieux, Coralie ^{[8
]}

Hermine, Olivier ^{[1
,3
]}

Lemonnier, Francois ^{[1
]}

机构：

[1] Univ Paris 05, Hop Necker, Assistance Publ Hop Paris, Serv Hematol Adulte,Inst Imagine, Paris, France

[2] Univ Paris 05, Hop Cochin, Assistance Publ Hop Paris, Serv Hematol Biol, Paris, France

[3] INSERM 1163, Inst Imagine, Paris, France

[4] Univ Paris 05, Hop Cochin, Assistance Publ Hop Paris, Serv Hematol Biol, Paris, France

[5] Hop Necker Enfants Malad, Assistance Publ Hop Paris, Inst Imagine, Dept Biotherapie, Paris, France

[6] Univ Paris Est, Hop Henri Mondor, Assistance Publ Hop Paris, INSERM,U955,Dept Pathol, Creteil, France

[7] Hop Necker Enfants Malad, Assistance Publ Hop Paris, Serv Cytogenet, Paris, France

[8] Univ Paris 05, Hop Necker, Assistance Publ Hop Paris, Serv Hematol Biol, Paris, France

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2015年 / 168卷 / 06期

关键词：

angioimmunoblastic T cell lymphoma; TET2; mutation; 5-azacytidine; epigenetic; CHRONIC MYELOMONOCYTIC LEUKEMIA; MUTATIONS; FEATURES;

D O I：

10.1111/bjh.13170

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：913 / 916

页数：4

共 10 条

[1] IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma [J].

Cairns, Rob A. ;

Iqbal, Javeed ;

Lemonnier, Francois ;

Kucuk, Can ;

de Leval, Laurence ;

Jais, Jean-Philippe ;

Parrens, Marie ;

Martin, Antoine ;

Xerri, Luc ;

Brousset, Pierre ;

Chan, Li Chong ;

Chan, Wing-Chung ;

Gaulard, Philippe ;

Mak, Tak W. .

BLOOD, 2012, 119 (08) :1901-1903

[2] TET2 and DNMT3A Mutations in Human T-Cell Lymphoma [J].

Couronne, Lucile ;

Bastard, Christian ;

Bernard, Olivier A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (01) :95-96

[3] Occurrence of angioimmunoblastic T cell lymphoma in a patient with chronic myelomonocytic leukemia features [J].

Gaulier, A ;

Jary-Bourguignat, L ;

Serna, R ;

Pulik, M ;

Davi, F ;

Raphaël, M .

LEUKEMIA & LYMPHOMA, 2000, 40 (1-2) :197-+

[4] Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification [J].

Ito, Shinsuke ;

D'Alessio, Ana C. ;

Taranova, Olena V. ;

Hong, Kwonho ;

Sowers, Lawrence C. ;

Zhang, Yi .

NATURE, 2010, 466 (7310) :1129-U151

[5] Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia [J].

Itzykson, Raphael ;

Kosmider, Olivier ;

Renneville, Aline ;

Gelsi-Boyer, Veronique ;

Meggendorfer, Manja ;

Morabito, Margot ;

Berthon, Celine ;

Ades, Lionel ;

Fenaux, Pierre ;

Beyne-Rauzy, Odile ;

Vey, Norbert ;

Braun, Thorsten ;

Haferlach, Torsten ;

Dreyfus, Francois ;

Cross, Nicholas C. P. ;

Preudhomme, Claude ;

Bernard, Olivier A. ;

Fontenay, Michaela ;

Vainchenker, William ;

Schnittger, Susanne ;

Birnbaum, Daniel ;

Droin, Nathalie ;

Solary, Eric .

JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (19) :2428-+

[6] Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters [J].

Lemonnier, Francois ;

Couronne, Lucile ;

Parrens, Marie ;

Jais, Jean-Philippe ;

Travert, Marion ;

Lamant, Laurence ;

Tournillac, Olivier ;

Rousset, Therese ;

Fabiani, Bettina ;

Cairns, Rob A. ;

Mak, Tak ;

Bastard, Christian ;

Bernard, Olivier A. ;

de Leval, Laurence ;

Gaulard, Philippe .

BLOOD, 2012, 120 (07) :1466-1469

[7] Clinical, biologic, and pathologic features in 157 patients with angioimmunoblastic T-cell lymphoma treated within the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials [J].

Mourad, Nathalie ;

Mounier, Nicolas ;

Briere, Josette ;

Raffoux, Emmanuel ;

Delmer, Alain ;

Feller, Alfred ;

Meijer, Chris J. L. M. ;

Emile, Jean-Francois ;

Bouabdallah, Reda ;

Bosly, Andre ;

Diebold, Jacques ;

Haioun, Corinne ;

Coiffier, Bertrand ;

Gisselbrecht, Christian ;

Gaulard, Philippe .

BLOOD, 2008, 111 (09) :4463-4470

[8] TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis [J].

Quivoron, Cyril ;

Couronne, Lucile ;

Della Valle, Veronique ;

Lopez, Cecile K. ;

Plo, Isabelle ;

Wagner-Ballon, Orianne ;

Do Cruzeiro, Marcio ;

Delhommeau, Francois ;

Arnulf, Bertrand ;

Stern, Marc-Henri ;

Godley, Lucy ;

Opolon, Paule ;

Tilly, Herve ;

Solary, Eric ;

Duffourd, Yannis ;

Dessen, Philippe ;

Merle-Beral, Helene ;

Florence Nguyen-Khac ;

Fontenay, Michaela ;

Vainchenker, William ;

Bastard, Christian ;

Mercher, Thomas ;

Bernard, Olivier A. .

CANCER CELL, 2011, 20 (01) :25-38

[9] Somatic RHOA mutation in angioimmunoblastic T cell lymphoma [J].

Sakata-Yanagimoto, Mamiko ;

Enami, Terukazu ;

Yoshida, Kenichi ;

Shiraishi, Yuichi ;

Ishii, Ryohei ;

Miyake, Yasuyuki ;

Muto, Hideharu ;

Tsuyama, Naoko ;

Sato-Otsubo, Aiko ;

Okuno, Yusuke ;

Sakata, Seiji ;

Kamada, Yuhei ;

Nakamoto-Matsubara, Rie ;

Nguyen Bich Tran ;

Izutsu, Koji ;

Sato, Yusuke ;

Ohta, Yasunori ;

Furuta, Junichi ;

Shimizu, Seiichi ;

Komeno, Takuya ;

Sato, Yuji ;

Ito, Takayoshi ;

Noguchi, Masayuki ;

Noguchi, Emiko ;

Sanada, Masashi ;

Chiba, Kenichi ;

Tanaka, Hiroko ;

Suzukawa, Kazumi ;

Nanmoku, Toru ;

Hasegawa, Yuichi ;

Nureki, Osamu ;

Miyano, Satoru ;

Nakamura, Naoya ;

Takeuchi, Kengo ;

Ogawa, Seishi ;

Chiba, Shigeru .

NATURE GENETICS, 2014, 46 (02) :171-+

[10]

Vardiman JW., 2008, WHO CLASSIFICATION T

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