Spermatic mitochondria: role in oxidative homeostasis, sperm function and possible tools for their assessment

被引：36
作者：
de Agostini Losano, Joao Diego [1 ]
Ramos Angrimani, Daniel de Souza [1 ]
Leite, Roberta Ferreira [1 ]
Simoes da Silva, Barbara do Carmo [1 ]
Barnabe, Valquiria Hyppolito [1 ]
Nichi, Marcilio [1 ]
机构：
[1] Univ Sao Paulo, Dept Anim Reprod, Coll Vet Med & Anim Sci, Ave Prof Orlando Marques de Paiva 87, BR-05508270 Sao Paulo, Brazil
来源：
ZYGOTE | 2018年 / 26卷 / 04期
基金：
巴西圣保罗研究基金会;
关键词：
Glycolysis; Mitochondrion; Oxidative phosphorylation; Reactive Oxygen Species; Sperm; INTRACELLULAR CALCIUM; UNCOUPLING PROTEINS; MAMMALIAN SPERM; FLOW-CYTOMETRY; LIPID-PEROXIDATION; DNA FRAGMENTATION; ATPASE ACTIVITY; CELL VIABILITY; STRESS; CRYOPRESERVATION;
D O I：
10.1017/S0967199418000242
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Despite sperm mitochondrial relevance to the fertilization capacity, the processes involved in the production of ATP and functional dynamics of sperm mitochondria are not fully understood. One of these processes is the paradox involved between function and formation of reactive oxygen species performed by the organelle. Therefore, this review aimed to provide data on the role of sperm mitochondria in oxidative homeostasis and functionality as well the tools to assess sperm mitochondrial function.
引用
收藏
页码：251 / 260
页数：10
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